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Taylor, S. T.; Ellison, J. A.; Franka, R.; Marissen, W. E.; Rupprecht, C.. |
Rabies is an acute progressive encephalitis responsible for over 55,000 human fatalities each year. This zoonosis is preventable, if prompt medical intervention includes wound care and both active and passive immunization. Approximately 10 million people receive rabies post-exposure prophylaxis (PEP) annually. The World Health Organization recommends the administration of human and/or equine derived antirabies immune globulin (HRIG and ERIG) as well as cell culture vaccine for modern PEP in humans. However, in many developing regions where canine rabies is enzootic, alternative solutions for passive immunization are necessary due to the cost prohibitive, limited supply of HRIG and ERIG. Such disparities have prompted the development of anti-RABV monoclonal... |
Tipo: Info:eu-repo/semantics/article |
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Ano: 2013 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/246 |
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