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Protective effect of bronchial challenge with hypertonic saline on nocturnal asthma BJMBR
Borges,M.C.; Ferraz,E.; Terra-Filho,J.; Vianna,E.O..
Inhalation of hypertonic saline (HS) causes bronchoconstriction in asthmatic subjects. Repeated inhalation of HS leads to substantially reduced bronchoconstriction, known as the refractory period. Refractoriness due to different stimuli has also been described (cross-refractoriness). Nocturnal asthma is defined as an increase in symptoms, need for medication, airway responsiveness, and/or worsening of lung function that usually occurs from 4 to 6 am. Our objective was to determine the effect of refractoriness on nocturnal asthma. The challenge test consisted of inhalations of 4.5% saline with increasing durations until a reduction of 20% in forced expiratory volume in 1 s (FEV1) (PD20HS) or total time of 15.5 min. Twelve subjects with nocturnal asthma were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Refractory period; Bronchial challenge; Hypertonic saline; Bronchial provocation test.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000300006
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Biomass smoke COPD has less tomographic abnormalities but worse hypoxemia compared with tobacco COPD BJMBR
Meneghini,A.C.; Koenigkam-Santos,M.; Pereira,M.C.; Tonidandel,P.R.; Terra-Filho,J.; Cunha,F.Q.; Menezes,M.B. de; Vianna,E.O..
Special attention has emerged towards biomass smoke-induced chronic obstructive pulmonary disease (COPD), providing new knowledge for prevention and therapeutic approach of non-smoker COPD patients. However, the understanding of biomass smoke COPD is still limited and somewhat controversial. The aim of the present study was to compare COPD exclusively caused by tobacco smoking with COPD exclusively caused by environmental or occupational exposures. For this cross-sectional study, COPD patients were recruited from outpatient clinics and formed two groups: non-smoker COPD group (n=16) with exposure to biomass smoke who did not smoke cigarette and tobacco smoker COPD group (n=15) with people who did not report biomass smoke exposure. Subjects underwent...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic obstructive pulmonary disease; Biomass; Tobacco.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000500601
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Pulmonary function, cholinergic bronchomotor tone, and cardiac autonomic abnormalities in type 2 diabetic patients BJMBR
Melo,E.; Vianna,E.O.; Gallo Jr.,L.; Foss,M.C.; Terra-Filho,J..
This prospective study analyzed the involvement of the autonomic nervous system in pulmonary and cardiac function by evaluating cardiovascular reflex and its correlation with pulmonary function abnormalities of type 2 diabetic patients. Diabetic patients (N = 17) and healthy subjects (N = 17) were evaluated by 1) pulmonary function tests including spirometry, He-dilution method, N2 washout test, and specific airway conductance (SGaw) determined by plethysmography before and after aerosol administration of atropine sulfate, and 2) autonomic cardiovascular activity by the passive tilting test and the magnitude of respiratory sinus arrhythmia (RSA). Basal heart rate was higher in the diabetic group (87.8 ± 11.2 bpm; mean ± SD) than in the control group (72.9...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diabetes mellitus; Autonomic nervous system; Autonomic neuropathy; Heart rate variability; Blood pressure variability.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000300002
Registros recuperados: 3
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