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Sesquiterpene lactone-containing extracts from two chicory cultivars show different anthelmintic activity in vitro against Ostertagia ostertagi Organic Eprints
Peña-Espinoza, Miguel; Boas, Ulrik; Williams , Andrew R.; Thamsborg , Stig M.; Enemark, Heidi L..
Mechanisms behind reported in vivo anthelmintic effects of chicory (Cichorium intybus) in ruminants are poorly understood but it is likely that plant compounds, like sesquiterpene lactones (SL), play a role. Objectives: The aim was to test the inhibitory activity of SL-containing extracts from two chicory cultivars on free-living and parasitic stages of Ostertagia ostertagi. Methods: Leaves from chicory cv. Spadona and cv. Puna II were freeze-dried and SL extracted with methanol/water. Resulting extracts were incubated with cellulase enzyme and SL were purified from other plant compounds by normal solid-phase extraction. Purified extracts were dissolved in DMSO. O. ostertagi eggs from a mono-infected calf were hatched and first-stage larvae (L1) were...
Tipo: Conference paper, poster, etc. Palavras-chave: Feeding and growth; Health and welfare.
Ano: 2015 URL: http://orgprints.org/29398/1/Pe%C3%B1a-Espinoza%20et%20al_in%20vitro_WAAVP2015.pdf
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