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| Roşca,A.E.; Stoian,I.; Badiu,C.; Gaman,L.; Popescu,B.O.; Iosif,L.; Mirica,R.; Tivig,I.C.; Stancu,C.S.; Căruntu,C.; Voiculescu,S.E.; Zăgrean,L.. |
| Supraphysiological administration of anabolic androgenic steroids has been linked to increased blood pressure. The widely distributed amino acid taurine seems to be an effective depressor agent in drug-induced hypertension. The purpose of this study was to assess the impact of chronic high dose administration of nandrolone decanoate (DECA) and taurine on blood pressure in rats and to verify the potentially involved mechanisms. The study was conducted in 4 groups of 8 adult male Wistar rats, aged 14 weeks, treated for 12 weeks with: DECA (A group); vehicle (C group); taurine (T group), or with both drugs (AT group). Systolic blood pressure (SBP) was measured at the beginning of the study (SBP1), 2 (SBP2) and 3 months (SBP3) later. Plasma... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Anabolic androgenic steroids; Nandrolone decanoate; Taurine; Blood pressure; Angiotensin-converting enzyme; Nitric oxide. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000600706 |
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