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	Provedor de dados BJMBR (1) Autor Bermek,E. (1) Sener,A. (1) Tiryaki,D. (1) Turker-Sener,L. (1) Yalcintepe,L. (1) Yetkin,G. (1) Mais... Palavra-chave ADP-ribosylation (1) NAD+ (1) NAD+ glycohydrolase (1) Poly(ADP-ribose) polymerase (1) Rectal cancer (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2005 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Changes in NAD/ADP-ribose metabolism in rectal cancer BJMBR Yalcintepe,L.; Turker-Sener,L.; Sener,A.; Yetkin,G.; Tiryaki,D.; Bermek,E.. The extent of ADP-ribosylation in rectal cancer was compared to that of the corresponding normal rectal tissue. Twenty rectal tissue fragments were collected during surgery from patients diagnosed as having rectal cancer on the basis of pathology results. The levels of ADP-ribosylation in rectum cancer tissue samples (95.9 ± 22.1 nmol/ml) was significantly higher than in normal tissues (11.4 ± 4 nmol/ml). The level of NAD+ glycohydrolase and ADP-ribosyl cyclase activities in rectal cancer and normal tissue samples were measured. Cancer tissues had significantly higher NAD+ glycohydrolase and ADP-ribosyl cyclase activities than the control tissues (43.3 ± 9.1 vs 29.2 ± 5.2 and 6.2 ± 1.6 vs 1.6 ± 0.4 nmol mg-1 min-1). Approximately 75% of the NAD+... Tipo: Info:eu-repo/semantics/article Palavras-chave: Rectal cancer; ADP-ribosylation; NAD+; NAD+ glycohydrolase; Poly(ADP-ribose) polymerase. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000300006 Registros recuperados: 1 Primeira ... 1 ... Última

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