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| Naito,Yuji; Shimozawa,Makoto; Manabe,Hiroki; Kuroda,Masaaki; Tomatsuri,Naoya; Uchiyama,Kazuhiko; Takagi,Tomohisa; Yoshida,Norimasa; Yoshikawa,Toshikazu. |
| Red wine polyphenolic compounds have been demonstrated to possess antioxidant properties, and several studies have suggested that they might constitute a relevant dietary factor in the protection from coronary heart disease. The aim of the present study is to examine whether red wine extracts (RWE) can ameliorate oxysterol-induced endothelial response, and whether inhibition of adhesion molecule expression is involved in monocyte adhesion to endothelial cells. Surface expression and mRNA levels of adhesion molecules (intercellular adhesion molecule 1 and vascular cell adhesion molecule 1) were determined by ELISA and RT-PCR performed on human aortic endothelial cells (HAEC) monolayers stimulated with 7b-hydroxycholesterol or 25-hydroxycholesterol.... |
| Tipo: Journal article |
Palavras-chave: Adhesion molecule; Monocyte-endothelial cell interaction; Oxysterol; Red wine extract. |
| Ano: 2004 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000200009 |
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