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Shah,Rehmat; Subhan,Fazal; Sultan,Syed Muhammad; Haq,Matiul; Ahmad,Hussain; Khan,Qasim Riaz; Ali,Gowhar; Ullah,Sami; Ullah,Ihsan. |
Antipsychotic Drugs (APDs) are being widely prescribed to treat various disorders, including schizophrenia and bipolar disorder; however, abnormal glucose metabolism and weight gain have been reported with Atypical Anti-Psychotic drugs (AAPDs) that can lead to insulin-resistance and type 2 diabetes mellitus. The study was designed to assess various biochemical parameters including insulin and blood sugar before and after exposure to APDs in order to exclude the involvement of psychiatric disorders and certain other factors in metabolic dysregulations. Fifty seven APDs-naïve patients with first episode psychosis were divided into six groups who received olanzapine, quetiapine, risperidone, aripiprazole, haloperidol or combination of olanzapine with... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Olanzapine; Quetiapine; Risperidone; Antipsychotics; Pancreas; Insulin. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100535 |
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Shah,Rehmat; Subhan,Fazal; Sultan,Sayed Mohammad; Ali,Gowhar; Ullah,Ihsan; Ullah,Sami. |
Olanzapine and risperidone are widely prescribed atypical antipsychotics used in the treatment of schizophrenia and various other psychiatric disorders. Both of these drugs have been extensively reported to cause Type 2 diabetes mellitus and pancreatitis, however, the mechanism of olanzapine and risperidone-induced toxicity has not been so far unveiled. We, therefore, compared the streptozocin-induced pancreatic damage with that of pancreas isolated from olanzapine and risperidone treated rats. It was noticed that fibrotic growth, necrosis and derangement of the pancreatic islet cells caused by streptozocin were more pronounced than olanzapine and risperidone. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Histopathology/pancreas; Antipsychotic drugs/evaluation; Olanzapine; Risperidone. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300622 |
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Sajjad Haider,Muhammad; Maclaurin,Angus; Ali Chaudhry,Amjad; Mushtaque,Muhammad; Ullah,Sami. |
Grazing management of rangeland systems has not been well researched in Pakistan; grazing system the most sustainable is not known. In order to evaluate various grazing systems, a study was performed at Pabbi Hills Reserve Forest, Kharian, Punjab. Four simulated grazing treatments, viz. ungrazed control, continuous grazing, seasonal deferred grazing, and rotational deferred grazing, were tested in a randomized complete block design with four replicates. Response variables included species composition, fresh herbage yield, dry herbage yield of grasses and forbs, basal cover, and ground cover. Of the three grazing systems, the six-month seasonal deferred grazing system resulted in a marked increase in basal cover, but had no changes in relative species... |
Tipo: Journal article |
Palavras-chave: Sustainable rangeland system; Basal cover; Species composition; Herbage production; Ground cover; Six-month seasonal deferred grazing system. |
Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392011000400010 |
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Ali,Amjed; Ullah,Sami. |
Seed yield and achene oil yield are the main determinants for N application rates rather than seed composition. Nitrogen plays a critical role in producing unsaturated fatty acids (oleic and linoleic acids), which are the main factors determining sunflower oil quality (Helianthus annuus L.). Studies were conducted on the effect of N fertilization on seed yield, achene oil yield, and quality parameters of sunflower hybrids for two successive years (2010 and 2011) in a split plot arrangement under a randomized complete block design. The hybrids (Hysun-33 & S-278) and N levels (0, 75, 150, and 225 kg ha-1) were allotted in main and sub-plots, respectively. Increasing N levels resulted in steady increases in yield, protein contents and linoleic acid,... |
Tipo: Journal article |
Palavras-chave: Fertilization; Linoleic acid; Oleic acid; Palmitic acid; Helianthus annuus. |
Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392012000400016 |
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