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A semi-automatic computerized method to measure baroreflex-mediated heart rate responses that reduces interobserver variability BJMBR
Soares,P.P.S.; Ushizima,M.R.; Krieger,E.M.; Irigoyen,M.C.C..
Arterial baroreflex sensitivity estimated by pharmacological impulse stimuli depends on intrinsic signal variability and usually a subjective choice of blood pressure (BP) and heart rate (HR) values. We propose a semi-automatic method to estimate cardiovascular reflex sensitivity to bolus infusions of phenylephrine and nitroprusside. Beat-to-beat BP and HR time series for male Wistar rats (N = 13) were obtained from the digitized signal (sample frequency = 2 kHz) and analyzed by the proposed method (PRM) developed in Matlab language. In the PRM, time series were low-pass filtered with zero-phase distortion (3rd order Butterworth used in the forward and reverse direction) and presented graphically, and parameters were selected interactively. Differences...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Baroreflex sensitivity; Heart rate; Blood pressure; Phenylephrine; Nitroprusside.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000600018
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Critical analysis of autoregressive and fast Fourier transform markers of cardiovascular variability in rats and humans BJMBR
Silva,G.J.J.; Ushizima,M.R.; Lessa,P.S.; Cardoso,L.; Drager,L.F.; Atala,M.M.; Consolim-Colombo,F.M.; Lopes,H.F.; Cestari,I.A.; Krieger,J.E.; Krieger,E.M..
The autonomic nervous system plays an important role in physiological and pathological conditions, and has been extensively evaluated by parametric and non-parametric spectral analysis. To compare the results obtained with fast Fourier transform (FFT) and the autoregressive (AR) method, we performed a comprehensive comparative study using data from humans and rats during pharmacological blockade (in rats), a postural test (in humans), and in the hypertensive state (in both humans and rats). Although postural hypotension in humans induced an increase in normalized low-frequency (LFnu) of systolic blood pressure, the increase in the ratio was detected only by AR. In rats, AR and FFT analysis did not agree for LFnu and high frequency (HFnu) under basal...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Fast Fourier transform; Autoregressive model; Hypertension; SHR; Pharmacological blockade; Tilt test.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000400012
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