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Production of 5-hydroxy-7-methoxy-4-methylphthalide in a culture of Penicillium crustosum Anais da ABC (AABC)
Valente,Angela M.M.P.; Ferreira,Antonio G.; Daolio,Cristina; Rodrigues Filho,Edson; Boffo,Elisangela F.; Souza,Antonia Q.L.; Sebastianes,Fernanda L.S.; Melo,Itamar S..
The chemical reactions carried out by microorganisms have been used as a tool in modern chemistry. This paper reports the production of mycophenolic acid and a new phthalide by the endophytic fungus Penicillium crustosum obtained from coffee seeds. The fungus was cultivated in a liquid medium for a period of seven days and after that the culture medium was divided into four treatments: A, B, C and D, to which different organic substances were added. Treatment A was maintained as the control to evaluate the occurrence of biotransformation. Organic acids were added to the culture media of treatments B (ferulic and quinic acids) and C [cinnamic and 3,4-(methylenedioxy) cinnamic acids], and caffeine was added in the treatment D. All these organic compounds...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Coffee; Endophytic fungus; Mycophenolic acid; Penicillium crustosum; 5-hydroxy-7-methoxy-4-methylphthalide.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000200487
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