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	Provedor de dados BABT (1) BJPS (1) Autor Valente,Eduardo Sarmento (2) Campos,Tarcisio Passos Ribeiro de (1) Cuperschmid,Ethel Mizrahy (1) Ferreira,Andréa Vidal (1) Santos,Raquel Gouvêa dos (1) Silva,Juliana Batista da (1) Silveira,Marina Bicalho (1) Soares,Marcella Araugio (1) Waquil,Samira Soares (1) Mais... Palavra-chave Bone imaging (1) Brachytherapy (1) Cancer control (1) Ceramic seeds (1) HeLa cells (1) Holmium (1) Radiopharmaceuticals/biodistribution (1) Sodium fluoride 18F/production (1) Sodium fluoride 18F/quality control (1) Sodium fluoride. 18F/dosimetry (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2011 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Evaluation of hela cell lineage response to β radiation from Holmium-166 embedded in ceramic seeds BABT Valente,Eduardo Sarmento; Cuperschmid,Ethel Mizrahy; Campos,Tarcisio Passos Ribeiro de. This work studied the effects of β radiation of Ho-166 embedded in ceramic seeds on HeLa cells. Methodology consisted in the production of ceramic seeds with holmium-165 by sol-gel route. Chemical and physical characterizations of the seeds were performed. Subsequently, nuclear characterization was performed by gamma spectrometry. Experimental and theoretical activities were defined and initial dose rate were evaluated by MIRD (Medical Internal Radiation Dose Committee) methodology. The seeds were placed in confluent culture flasks and remained for six radionuclide half-lives. Biological results were represented by a clean 6 mm diameter area around the seed where the tumour cells were killed. The initial dose rate was 15.5 Gy. h-1. The maximum absorbed... Tipo: Info:eu-repo/semantics/article Palavras-chave: Brachytherapy; Ceramic seeds; Holmium; Cancer control; HeLa cells. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000500013 Synthesis, quality control and dosimetry of the radiopharmaceutical 18F-sodium fluoride produced at the Center for Development of Nuclear Technology - CDTN BJPS Silveira,Marina Bicalho; Soares,Marcella Araugio; Valente,Eduardo Sarmento; Waquil,Samira Soares; Ferreira,Andréa Vidal; Santos,Raquel Gouvêa dos; Silva,Juliana Batista da. 18F-Sodium fluoride (Na18F) is a radiopharmaceutical used for diagnosis in nuclear medicine by positron emission tomography (PET) imaging. Bone scintigraphy is normally performed using 99mTc-MDP. However, 18F PET scans promise high quality imaging with increased resolution and improved sensitivity and specificity. In order to make available a tool for more specific studies of tumors and non-oncological diseases of bone tissue, the UPPR/CDTN team undertook the production and quality control of Na18F injectable solution with the physical-chemical, microbiological and biological characteristics recommended in the U.S. Pharmacopeia. Na18F radiochemical purity was 96.7 ± 1.3 %, with Rf= 0.026 ± 0.006. The product presented a pH of 5.3 ± 0.6, half life of 109.0... Tipo: Info:eu-repo/semantics/article Palavras-chave: Radiopharmaceuticals/biodistribution; Sodium fluoride 18F/production; Sodium fluoride 18F/quality control; Sodium fluoride. 18F/dosimetry; Bone imaging. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300021 Registros recuperados: 2 Primeira ... 1 ... Última

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