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	Provedor de dados Nature Precedings (1) Autor Dmitry A. Smagin (1) Natalia N. Kudryavtseva (1) Nelly A. Popova (1) Svetlana I. Ilnitskaya (1) Valery P. Nikolin (1) Vasily N. Kaledin (1) Mais... Palavra-chave Cancer (1) Neuroscience (1) Pharmacology (1) Tipo do documento Manuscript (1) Ano 2009 (1) País United Kingdom (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Limiting effect of diazepam on Lewis lung carcinoma metastasis in anxious male mice Nature Precedings Vasily N. Kaledin; Svetlana I. Ilnitskaya; Valery P. Nikolin; Nelly A. Popova; Dmitry A. Smagin; Natalia N. Kudryavtseva. _Aim:_ It has been shown previously that chronic social defeat stress produces development of strong anxiety and increases intensity of experimental metastasis in the losers in comparison with the control mice. The question was: is it possible to decrease the number of metastases in the losers by chronic or acute diazepam treatment. _Materials and Methods._ Sensory contact model was used for generating male mice with repeated experience of social defeats or victories in daily agonistic interactions. Lewis Lung Carcinoma cells (LLC) were injected into the tail vein of animals after 10 days of agonistic interactions. Then mice were treated acutely or chronically (7 days) with diazepam (1 mg/kg, i.p). Number of metastases in the lung was calculated in 16 days... Tipo: Manuscript Palavras-chave: Cancer; Neuroscience; Pharmacology. Ano: 2009 URL: http://precedings.nature.com/documents/2748/version/1 Registros recuperados: 1 Primeira ... 1 ... Última

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