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| Marjani,Majid; Baghaei,Parvaneh; Malekmohammad,Majid; Tabarsi,Payam; Sharif-Kashani,Babak; Behzadnia,Neda; Mansouri,Davood; Masjedi,Mohammad Reza; Velayati,Ali Akbar. |
| Background:This study performed at the National Research Institute of Tuberculosis and Lung Disease, Tehran, Iran, aimed to evaluate the effect of concomitant pulmonary hypertension on the outcome of pulmonary tuberculosis.Methods:New cases of pulmonary tuberculosis were recruited for the study. Pulmonary hypertension was defined as systolic pulmonary arterial pressure ≥35 mm Hg estimated by transthoracic Doppler echocardiography. We assessed the relationship between pulmonary hypertension and mortality during the six-month treatment of tuberculosis.Results:Of 777 new cases of pulmonary tuberculosis, 74 (9.5%) had systolic pulmonary arterial pressure ≥35 mm Hg. Ten of them (13.5%) died during treatment compared to 5% of cases with pulmonary arterial... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tuberculosis; Pulmonary hypertension; Echocardiography; Survival. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500487 |
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| Merza,Muayad; Farnia,Parissa; Anoosheh,Sabar; Varahram,Mohammed; Kazampour,Mehdi; Pajand,Omid; Saeif,Shima; Mirsaeidi,Mehdi; Masjedi,Mohammad Reza; Velayati,Ali Akbar; Hoffner,Sven. |
| The natural resistance-associated macrophage protein (NRAMP1), Vitamin-D receptor (VDR) and Tumor necrosis factor (TNF-α) have been associated in susceptibility to tuberculosis, but the results have been inconsistent. This study aimed to determine the association of NRAMP1, VDR, and TNF-á variant with development of pulmonary tuberculosis (PTB) among Iranian patients. The single nucleotide polymorphisms (SNPs) at INT4, D543, 3'UTR of NRAMP1 gene, SNPs in restriction sites of BsmI, and FokI of the VDR gene and SNPs of TNF-α at -238,-308, -244,857,-863 positions were analyzed by PCR-RFLP among two groups of individual; patients with PTB (n=117) and healthy controls (n=60). Thereafter, the frequencies of extended haplotypes and diplotypes were estimated. No... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: NRAMP; VDR; TNF-α gene; Tuberculosis. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000400002 |
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