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| Ellison, J. A.; Johnson, S. R.; Kuzmina, N. K.; Gilbert, A. T.; Carson, W. C.; Blanton, J. D.; VerCauteren, K.; Rupprecht, C.. |
| Zoonotic disease surveillance is typically initiated after an animal pathogen has caused disease in humans. Early detection of potentially high-risk pathogens within animal hosts may facilitate medical interventions to cope with an emerging disease. To effectively spillover to a novel host, a pathogen may undergo genetic changes resulting in varying transmission potential in the new host and potentially to humans. Rabies virus (RABV) is one model pathogen to consider for studying the dynamics of emerging infectious diseases under both laboratory and field conditions. The evolutionary history of RABV is characterized by regularly documented spillover infections and a series of notable host-shifts. Within this context, enhanced field surveillance to improve... |
| Tipo: Info:eu-repo/semantics/article |
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| Ano: 2013 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/3164 |
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| Bender, S. C.; Bender, P.; Hausig, K.; Berentsen, A.; Bergman, D. L.; VerCauteren, K.. |
| It is estimated that less than 20% of domestic dogs on tribal lands in the United States are vaccinated against rabies. One potential method to increase vaccination rates may be the distribution of oral rabies vaccines (ORV). ONRAB® is the primary ORV bait used in Canada to vaccinate striped skunks and raccoons. Research has suggested the most common non-target animals that may ingest these baits are feral domestic dogs. To further investigate the potential use of ONRAB® ORV baits to vaccinate feral domestic dogs against rabies on tribal lands, we performed a flavor preference study to increase ORV acceptance. Seven bait flavors (bacon, cheese, dog food, hazelnut, marshmallow, peanut butter and sardine) were offered in pairs to 13 domestic dogs. Each dog... |
| Tipo: Info:eu-repo/semantics/article |
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| Ano: 2013 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/5388 |
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| Fry, T. L.; VanDalen, K.; Duncan, C.; VerCauteren, K.. |
| ONRAB® is a recombinant rabies vaccine used to as an oral vaccine in wildlife species such as: fox (Vulpes vulpes), raccoons (Procyon lotor), and striped skunks (Mepthis mephitis). The viral vector in the ONRAB® vaccine is human adenovirus type 5 (Had5) with the gene for rabies glycoprotein incorporated into its genome. Had5 is a relatively safe and well-studied virus, which is used in many vaccine formulations. Canadian researchers (e.g., Knowles et al. 2009) have conducted vaccine efficacy and safety studies using ONRAB® in 18 species of animals. Our research expands on the species previously evaluated. We studied the vaccine as it relates to its safety in wildlife species likely to contact the ONRAB® vaccine during oral rabies vaccine (ORV) campaigns in... |
| Tipo: Info:eu-repo/semantics/article |
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| Ano: 2013 |
URL: http://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/3077 |
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