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Vicente,J.D.; Santo,G.R.; Palin,G.C.; Reati,L.A.; Urano,T.K.; Trindade,W.A.; Amaral,P.F.G.P.; Gerônimo,E.; Otutumi,L.K.; Lourenço,E.L.B.; Dragunski,D.C.; Germano,R.M.. |
ABSTRACT This study aimed to macroscopically and microscopically evaluate the healing of skin wounds induced in rats by topical application of cassava polyamide biopolymer hydrogel. In total, 32 rats were used and divided into four groups (n= 8): negative control - saline solution; positive control - use of commercial ointment; experimental group - I - ointment + cassava hydrogel; experimental group - II - cassava hydrogel. A 1cm2 wound induced on the animals dorsum was treated and evaluated. At day 21 post-operation, the animals were sacrificed by anesthetic overdose, and then 1cm2 of cicatricial skin from the wound region was collected. The material was cut to evaluate healing. In the macroscopic evaluation, complete healing was observed at the end of 21... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cassava starch; Fibroplasias; Manihot esculenta; Skin. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300889 |
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