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Clinical and economic impact of generic versus brand name meropenem use in an intensive care unit in Colombia BJID
Ordóñez,Karen; Feinstein,Max M.; Reyes,Sergio; Hernández-Gómez,Cristhian; Pallares,Christian; Villegas,María V..
Abstract Background: Recent studies suggest that sustained use of generic antibiotics may be associated with clinical failure and emergence of antibacterial resistance. The present study was designed to determine the clinical outcome between the use of generic meropenem (GM) and brand-name meropenem (BNM). Additionally, this study evaluated the economic impact of GM and BNM to determine if the former represents a cost-effective alternative to the latter. Methods: Patients treated between January 2011 and May 2014 received GM while patients treated between June 2014 and March 2017 received BNM. Mortality was compared between groups. Total infection cost was defined by the cost of antimicrobial consumption, length of stay, and laboratory and imaging exams...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Generic drugs; Meropenem; Mortality; Costs; Critical care; Gram negative bacteria.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000400237
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