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	Provedor de dados BJID (1) Autor Biscione,Fernando Martin (1) Greco,Dirceu Bartolomeu (1) Machado,Danielle Pessoa (1) Ribeiro,Karina Mota (1) Tupinambás,Unaí (1) Westin,Mateus Rodrigues (1) Mais... Palavra-chave Genotyping techniques (1) HIV-1 (1) Highly active antiretroviral therapy (1) Multiple viral drug resistance (1) Salvage therapy (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2014 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Virologic and immunologic effectiveness of darunavir-based salvage therapy in HIV-1-infected adults in a Brazilian clinical practice setting: results of a multicenter and retrospective cohort study BJID Ribeiro,Karina Mota; Biscione,Fernando Martin; Westin,Mateus Rodrigues; Machado,Danielle Pessoa; Greco,Dirceu Bartolomeu; Tupinambás,Unaí. Background:Darunavir has been proven efficacious for antiretroviral-experienced HIV-1-infected patients in randomized trials. However, effectiveness of darunavir-based salvage therapy is understudied in routine care in Brazil.Methods:Retrospective cohort study of HIV-1-infected patients from three public referral centers in Belo Horizonte, who received a darunavir-based therapy between 2008 and 2010, after virologic failure. Primary endpoint was the proportion of patients with viral load <50 copies/mL at week 48. Change in CD4 cell count was also evaluated. Outcome measures were analyzed on an intent-to-treat basis applied to observational studies. Sensitivity analysis was conducted to evaluate the impact of missing data at week 48. Predictors of... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV-1; Highly active antiretroviral therapy; Salvage therapy; Multiple viral drug resistance; Genotyping techniques. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000100001 Registros recuperados: 1 Primeira ... 1 ... Última

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