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	Provedor de dados BJMBR (1) Autor A. Netto,C. (1) Cechetti,F. (1) Pereira,L.O. (1) Siqueira,I.R. (1) Worm,P.V. (1) Palavra-chave Chronic cerebral hypoperfusion (1) Hippocampus (1) Spatial memory (1) Striatum (1) Water maze (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última The modified 2VO ischemia protocol causes cognitive impairment similar to that induced by the standard method, but with a better survival rate BJMBR Cechetti,F.; Worm,P.V.; Pereira,L.O.; Siqueira,I.R.; A. Netto,C.. Permanent bilateral occlusion of the common carotid arteries (2VO) in the rat has been established as a valid experimental model to investigate the effects of chronic cerebral hypoperfusion on cognitive function and neurodegenerative processes. Our aim was to compare the cognitive and morphological outcomes following the standard 2VO procedure, in which there is concomitant artery ligation, with those of a modified protocol, with a 1-week interval between artery occlusions to avoid an abrupt reduction of cerebral blood flow, as assessed by animal performance in the water maze and damage extension to the hippocampus and striatum. Male Wistar rats (N = 47) aged 3 months were subjected to chronic hypoperfusion by permanent bilateral ligation of the common... Tipo: Info:eu-repo/semantics/article Palavras-chave: Chronic cerebral hypoperfusion; Spatial memory; Hippocampus; Striatum; Water maze. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001200007 Registros recuperados: 1 Primeira ... 1 ... Última

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