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| Qin,B.; Chen,H.; Gao,W.; Zhao,L.B.; Zhao,M.J.; Qin,H.X.; Chen,W.; Chen,L.; Yang,M.X.. |
| The aim of this study was to investigate the efficacy, acceptability, and tolerability of antidepressants in treating post-stroke depression (PSD) by performing a network meta-analysis of randomized controlled trials of the current literature. Eligible studies were retrieved from online databases, and relevant data were extracted. The primary outcome was efficacy as measured by the mean change in overall depressive symptoms. Secondary outcomes included discontinued treatment for any reason and specifically due to adverse events. Fourteen trials were eligible, which included 949 participants and 9 antidepressant treatments. Few significant differences were found for all outcomes. For the primary outcome, doxepin, paroxetine, and nortriptyline were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antidepressants; Post-stroke depression; Randomized controlled trials; Network meta-analysis. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000700601 |
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| Yu,J.; Luo,Y.; Yang,X.F.; Yang,M.X.; Yang,J.; Yang,X.S.; Zhou,J.; Gao,F.; He,L.T.; Xu,J.. |
| The current study aimed to investigate the effects of perinatal exposure to nonylphenol (NP) on delivery outcome of pregnant rats and subsequent inflammatory hepatic injury in newborn rats. The pregnant rats were divided into 2 groups: control group (corn oil) and NP exposure group. Thirty-four pregnant rats were administered NP or corn oil by gavage from the sixth day of pregnancy to 21 days postpartum, with blood samples collected at 12 and 21 days of pregnancy and 60 days after delivery. The NP concentration was measured by HPLC, with chemiluminescence used for detection of estrogen and progesterone levels. Maternal delivery parameters were also observed. Liver and blood of the newborn rats were collected and subjected to automatic biochemical detection... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nonylphenol; Hepatic injury; Delivery; Newborn rats. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016001200702 |
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