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	Provedor de dados BJMBR (1) Autor Jiang,L. (1) Liang,Y. (1) Yang,N. (1) Yang,P. (1) Yang,T. (1) Palavra-chave Cell apoptosis (1) Cell viability (1) Lung cancer (1) MicroRNA-486 (1) Propofol (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2017 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Propofol inhibits lung cancer cell viability and induces cell apoptosis by upregulating microRNA-486 expression BJMBR Yang,N.; Liang,Y.; Yang,P.; Yang,T.; Jiang,L.. Propofol is a frequently used intravenous anesthetic agent. Recent studies show that propofol exerts a number of non-anesthetic effects. The present study aimed to investigate the effects of propofol on lung cancer cell lines H1299 and H1792 and functional role of microRNA (miR)-486 in these effects. H1299 and/or H1792 cells were treated with or without propofol and transfected or not with miR-486 inhibitor, and then cell viability and apoptosis were analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and flow cytometry. The expression of miR-486 was determined by quantitative real-time polymerase chain reaction (qRT-PCR) with or without propofol treatment. Western blot was performed to analyze the protein expression of Forkhead... Tipo: Info:eu-repo/semantics/article Palavras-chave: Propofol; Lung cancer; Cell viability; Cell apoptosis; MicroRNA-486. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000100601 Registros recuperados: 1 Primeira ... 1 ... Última

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