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	Provedor de dados BJPS (2) Autor Uyar,Ahmet (2) Yener,Zabit (2) Demirtaş,Ömer Can (1) Huyut,Zübeyir (1) Kaya,Mehmet Salih (1) Keles,Ömer Faruk (1) Keleş,Ömer Faruk (1) Uslu,Baris Atalay (1) Yaman,Turan (1) Yıldızhan,Kenan (1) Çakir,Tahir (1) Mais... Palavra-chave Antioxidant (1) GPx1 (1) Methotrexate/Testes/induced damages (1) Oxidative stress (1) Pathology. (1) Radiation (1) SOD2 (1) Seed extract (1) Silymarin/effects (1) Tissue injury (1) Urtica dioica L (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2020 (1) 2018 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Protective effects of silymarin on methotrexate-induced damages in rat testes BJPS Yaman,Turan; Uyar,Ahmet; Kaya,Mehmet Salih; Keles,Ömer Faruk; Uslu,Baris Atalay; Yener,Zabit. Abstract The present study aimed to investigate the protective effects of silymarin (SMN), an antioxidant, on methotrexate (MTX)-induced damage in rat testes. Thirty-two Wistar albino rats were divided into four groups (n = 8): control, MTX (20 mg/kg, i.p. on days 1 and 5), SMN (200 mg/kg, orally), and MTX + SMN (20 mg/kg, i.p. on days 1 and 5 and SMN 200 mg/kg orally) groups. At the end of the 6-week trial period, histopathological, immunohistochemical, biochemical, and spermatological analyses were performed on testes tissues. Histopathologically, MTX-induced damage, including depletion of germ cell and loos of spermatozoa, was significantly improved with SMN treatment. Immunohistochemically, the immunoreactivity of glutathione peroxidase 1 (GPx1) and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Silymarin/effects; Methotrexate/Testes/induced damages; GPx1; SOD2; Pathology.. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000100618 Protective effects of Urtica dioica L. seed extract on liver tissue injury and antioxidant capacity in irradiated rats BJPS Yıldızhan,Kenan; Demirtaş,Ömer Can; Uyar,Ahmet; Huyut,Zübeyir; Çakir,Tahir; Keleş,Ömer Faruk; Yener,Zabit. Radiotherapy is often used for the treatment of cancer. However, it causes some side effects in patients. This study aimed to determine the hepatoprotective effects of Urtica dioica L. seed-extract (UDSE) in radiation-induced liver injury. Thirty-two male rats were randomly divided into 4 groups (n=8): control(C) group: no action was taken; radiation (R) group: irradiation was administrated at 5Gy single-fraction, radiation with UDSE(R+UDSE) group: irradiation was administrated at 5 Gy single-fraction and animals were fed pellets with 30 mL UDSE/kg; UDSE group: animals were fed pellets with 30 mL UDSE/kg. All of the experiments were performed in all of the groups over 10 days. Malondialdehyde (MDA) and reduced-glutathione (GSH) levels and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Radiation; Urtica dioica L; Seed extract; Oxidative stress; Antioxidant; Tissue injury. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100536 Registros recuperados: 2 Primeira ... 1 ... Última

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