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	Provedor de dados BJMBR (1) Autor Li,D.C. (1) Mao,Z.Q. (1) Yin,J. (1) Zhu,Z. (1) Palavra-chave Expression profile (1) Methylation (1) MicroRNA (1) Roux-en-Y gastric bypass (1) Type 2 diabetes mellitus (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2017 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Role of microRNAs in the treatment of type 2 diabetes mellitus with Roux-en-Y gastric bypass BJMBR Zhu,Z.; Yin,J.; Li,D.C.; Mao,Z.Q.. The aim of this study was to investigate the effect of Roux-en-Y gastric bypass (RYGB) on the peripheral blood microRNAs (miRNAs) of patients with type 2 diabetes mellitus (T2DM). miRNAs are small 20- to 22-nucleotide (nt) noncoding RNAs. They constitute a novel class of gene regulators that negatively regulate gene expression at the post-transcriptional level. miRNAs play an important role in several biological processes. Twelve patients with T2DM who were scheduled to undergo laparoscopic RYGB surgery were separated into two groups, using a body mass index of 30 kg/m2 as a cut-off point. Venous blood was collected before operation and 12 months after operation. A significant change was observed in the peripheral blood miRNA expression profile of both... Tipo: Info:eu-repo/semantics/article Palavras-chave: Expression profile; Methylation; MicroRNA; Roux-en-Y gastric bypass; Type 2 diabetes mellitus. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000300705 Registros recuperados: 1 Primeira ... 1 ... Última

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