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| Bessa,Thais Fontes; Cordeiro,Cynthia Azeredo; Gonçalves,Roberto Martins; Young,Lucy H.; Campos,Wesley R.; Oréfice,Fernando; Teixeira,Antônio L.. |
| This study aimed to investigate the serum levels of the cytokine TNF-α and its soluble receptors (sTNFR1 and sTNFR2) in patients with toxoplasmosis retinochoroidits (TR) and controls. 37 patients with TR and 30 subjects with positive serology for toxoplasmosis but without history and signs of uveitis were included in this study. Serum concentrations of TNF-α, sTNFR1, and sTNFR2 were determined by ELISA. Serum concentrations of TNF-α and sTNFR1 were similar in controls (mean ± SD median values; 56.57 ± 141.96 and 504.37 ± 163.87, respectively) and TR patients (mean ± SD values, 121.62 ± 217.56 and 511.15 ± 189.30, respectively). Serum concentrations of sTNFR2 were higher in the uveitis group when compared to the control group (respectively, mean ± SD... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Toxoplasmosis Uveitis; TNF-alpha; Soluble TNF receptors. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600007 |
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