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	Provedor de dados BJMBR (1) Autor Chen,Y. (1) Jin,Y. (1) Liu,C.F. (1) Yu,L.L. (1) Zhang,B. (1) Palavra-chave Circular RNA hsa_circ_0000523 (1) Colorectal cancer (1) Interference (1) Proliferation (1) Sponge (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2018 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Circular RNA hsa_circ_0000523 regulates the proliferation and apoptosis of colorectal cancer cells as miRNA sponge BJMBR Jin,Y.; Yu,L.L.; Zhang,B.; Liu,C.F.; Chen,Y.. Among the novel class of endogenous long non-coding RNAs, circular RNA (circRNA) is known as a key regulator in the development and progression of different cancers. Its function and mechanism in the tumorigenesis of colorectal cancer, however, has not been well studied. This study thus aimed to investigate potential regulation of colorectal cancer by circRNAs and the corresponding regulatory mechanism. We demonstrated that the expression of circRNA hsa_circ_0000523 (also known as circ_006229) was down-regulated in different colorectal cancer cell lines. It was also found that interference of hsa_circ_0000523 induced proliferation and suppressed apoptosis of colorectal cancer cells, the proliferation rate of which was reduced by the overexpression of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Circular RNA hsa_circ_0000523; Colorectal cancer; Proliferation; Sponge; Interference. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200611 Registros recuperados: 1 Primeira ... 1 ... Última

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