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Analysis of gene expression profiles in response to Sporisorium reilianum f. sp. zeae in maize (Zea mays L.) Electron. J. Biotechnol.
Yu,Tao; Wang,Zhenhua; Jin,Xiaochun; Liu,Xianjun; Kan,Shuaishuai.
Background Head smut of maize, which is caused by Sporisorium reilianum f. sp. zeae (Kühn), is a serious disease in maize. In order to reveal the molecular mechanism of the resistance to head smut in maize, a microarray containing ~ 14,850 probes was used to monitor the gene expression profiles between a disease resistant near isogenic line (NIL) and a highly susceptible inbred line after S. reilianum was injected with an artificial inoculation method. Results Levels of expression for 3,532 genes accounting for 23.8% of the total probes changed after inoculation. Gene Ontology analysis revealed that the differentially expressed genes participated in physiological and biochemical pathways. The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis...
Tipo: Journal article Palavras-chave: Differentially expressed genes; Head smut resistance gene; Maize; Microarray.
Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582014000500007
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Exosomes secreted from miRNA-29b-modified mesenchymal stem cells repaired spinal cord injury in rats BJMBR
Yu,Tao; Zhao,Cunju; Hou,Shouzhi; Zhou,Weijie; Wang,Baoxin; Chen,Yunzhen.
Exosomes, a kind of extracellular vesicle, are promising therapeutic agents for spinal cord injury (SCI). This article aimed to investigate effects of exosomes secreted from miRNA-29b-modified bone marrow mesenchymal stem cells (BMSCs) on SCI. Exosomes were extracted from BMSCs transfected with miRNA-29b or negative control (miR NC). SCI rats were injected intravenously with exosomes (control exosomes, miRNA-29b exosomes) and BMSCs (miR NC, miRNA-29b) through the tail vein. The expression of miRNA-29b in spinal cord tissues of SCI rats was detected by qRT-PCR. The hind limb motor function was evaluated by Basso Beattie Bresnahan (BBB) score. The histopathological damage and neuronal regeneration in spinal cord tissues was observed by HE staining and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: MiRNA-29b; Exosomes; Spinal cord injury; BMSCs.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019001200614
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