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A three-dimensional stochastic spatio-temporal model of cell spreading Nature Precedings
Yuguang P. Xiong; Padmini Rangamani; Benjamin Dubin-Thaler; Michael Sheetz; Ravi Iyengar.
Cell motility is important for many physiological processes and the underlying
biochemical reactions motility have been well characterized. Mathematical models, using
the biochemical reactions and focused on different types of spreading behavior have been
constructed and analyzed. In this study, we build on these previous models to develop a
three-dimensional stochastic model of isotropic spreading of mammalian fibroblasts. The model is composed of three actin remodeling reactions that occur stochastically in space and time and are regulated by membrane resistance forces. Numerical simulations indicate that the model qualitatively captures the experimentally observed isotropic cell...
Tipo: Manuscript Palavras-chave: Biotechnology; Molecular Cell Biology; Bioinformatics.
Ano: 2007 URL: http://precedings.nature.com/documents/62/version/2
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A Three dimesional stochastic spatio-temporal model of cell spreading Nature Precedings
Yuguang P. Xiong; Padmini Rangamani; Benjamin Dubin-Thaler; Michael Sheetz; Ravi Iyengar.
Cell motility is important for many physiological processes and the underlying
biochemical reactions motility have been well-characterized. Mathematical models, using
the biochemical reactions and focused on different types of spreading behavior have been
constructed and analyzed. In this study, we build on these previous models to develop a
three-dimensional stochastic model of isotropic spreading of mammalian fibroblasts. The model is composed of three actin remodeling reactions that occur stochastically in space and time and are regulated by membrane resistance forces. Numerical simulations indicate that the model qualitatively captures the experimentally observed isotropic cell...
Tipo: Manuscript Palavras-chave: Biotechnology; Molecular Cell Biology; Bioinformatics.
Ano: 2007 URL: http://precedings.nature.com/documents/62/version/1
Registros recuperados: 2
Primeira ... 1 ... Última
 

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