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| WANG,Chunmei; RUAN,Shiman; GU,Xunmei; ZHU,Bin. |
| Abstract This study investigated the antiviral activities of Radix Isatidis polysaccharide (RIP) against type II herpes simplex virus (HSV-2) in vitro. RIP was prepared from the Radix Isatidis root. The toxicity of RIP on Vero cells was detected. The direct killing effect of RIP on HSV-2, inhibitory effect of RIP on HSV-2 replication and inhibitory effect of RIP on HSV-2 adsorption were determined. Results showed that, RIP in concentration range of 25-800 mg/L had no toxic effect on Vero cells. RIP with different concentrations could not directly inactivate the HSV-2. The effective rates on inhibition of HSV-2 replication and adsorption in 800 mg/L RIP group were 71.57% and 48.37%, respectively, which were the highest among different groups. In conclusion,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Radix Isatidis; Polysaccharide; HSV-2. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612018000500180 |
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