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Evaluation of the effects of autohemotransfusion in arthritic rats induced by two doses of complete Freund´s adjuvant Biological Sciences
Lima, Mariana Machado; Silva, Lorena Gimenes da; Dantas, Jailson Araújo; Amado, Ciomar Aparecida Bersani; Spack Junior, Miguel; Zanoni, Jacqueline Nelisis.
 The aim the study was to evaluate the effects of autohemotransfusion in adjuvant-induced arthritis model by injections of high and low doses of Complete Freund´s Adjuvant (CFA). Male Holtzman rats (200-230g) were distributed in six groups: control (C); control treated by autohemotransfusion (CT); CFA induced arthritis 0.5% w/v (AIA); CFA induced arthritis 0.5% w/v treated with autohemotransfusion (AIAT); CFA induced arthritis 0.1% w/v (AS) and CFA induced arthritis 0.1% w/v treated with autohemotransfusion (AST). The number of leukocytes, the weight of different organs and the paw volume were analyzed. The autohemotransfusion without erythrocytes promoted a reduction in the number of leukocytes in AIAT and AST when compared to AIA (p < 0.001). In the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Adjuvant Immunologic; Rats; Induced rheumatoid arthritis..
Ano: 2019 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/36978
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