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	Provedor de dados BJM (1) BJPS (1) Autor Zavascki,Alexandre Prehn (2) Antunes,Marina Venzon (1) Barth,Afonso Luis (1) Castilhos,Juliana Kich (1) Dillenburg,Thaís Luise (1) Gaspareto,Patrick Barcelos (1) Linden,Rafael (1) Martins,Andreza Francisco (1) Scribel,Letícia (1) Verza,Simone Gasparin (1) Mais... Palavra-chave Glucose solutions (1) Imipenem resistance (1) LC-MS/MS (1) Metallo-beta-lactamase (1) Polymyxin (1) Pseudomonas aeruginosa (1) Saline solutions (1) Stability (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2020 (1) 2007 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Ocurrence of blaSPM-1 and blaIMP-1 genes of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa from three universitary hospitals in the city of Porto Alegre, Brazil BJM Gaspareto,Patrick Barcelos; Martins,Andreza Francisco; Zavascki,Alexandre Prehn; Barth,Afonso Luis. We described the ocurrence of metallo-beta-lactamases (MBL) genes blaSPM-1 and blaIMP-1 in clinical isolates of Pseudomonas aeruginosa resistant to imipenem and/or ceftazidime obtained from three universitary hospitals in the city of Porto Alegre, Brazil. The MBL production was screened by phenotypic test and the genes were detected by PCR. Tipo: Info:eu-repo/semantics/article Palavras-chave: Pseudomonas aeruginosa; Imipenem resistance; Metallo-beta-lactamase. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000100022 Evaluation of the stability of Polymyxin B in saline and glucose solutions using LC-MS/MS BJPS Castilhos,Juliana Kich; Dillenburg,Thaís Luise; Antunes,Marina Venzon; Scribel,Letícia; Zavascki,Alexandre Prehn; Linden,Rafael; Verza,Simone Gasparin. Polymyxins are a group of antibacterial substances and have remained the drugs of choice for treatment of resistant Gram-negative bacilli. Polymyxin B is administered by intravenous infusion and requires the reconstitution of lyophilized powder with 0.9% saline or 5% glucose solutions. To date, there is little information about polymyxin stability in different infusions solutions, especially at 40 ºC, a temperature that is recommended to study drug stability as it accelerates degradation reactions. Therefore, in this work an analytical method using LC-MS/MS was developed, validated and applied to determine the stability of polymyxin B diluted in 0.9% saline or 5% glucose solutions at 25 ºC and 40 ºC. The stability of polymyxin B solutions was evaluated... Tipo: Info:eu-repo/semantics/article Palavras-chave: Polymyxin; Stability; LC-MS/MS; Glucose solutions; Saline solutions. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100537 Registros recuperados: 2 Primeira ... 1 ... Última

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