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	Provedor de dados BJMBR (1) Autor Du,F. (1) Wang,H.X. (1) Wang,L. (1) Zhang,H.M. (1) Zhang,W.J. (1) Palavra-chave Chemotherapy (1) Circulating endothelial progenitor cells (1) Multiple myeloma (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2015 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Changes in circulating endothelial progenitor cells predict responses of multiple myeloma patients to treatment with bortezomib and dexamethasone BJMBR Wang,L.; Du,F.; Zhang,H.M.; Zhang,W.J.; Wang,H.X.. Four cycles of chemotherapy are required to assess responses of multiple myeloma (MM) patients. We investigated whether circulating endothelial progenitor cells (cEPCs) could be a biomarker for predicting patient response in the first cycle of chemotherapy with bortezomib and dexamethasone, so patients might avoid ineffective and costly treatments and reduce exposure to unwanted side effects. We measured cEPCs and stromal cell-derived factor-1α (SDF-1α) in 46 MM patients in the first cycle of treatment with bortezomib and dexamethasone, and investigated clinical relevance based on patient response after four 21-day cycles. The mononuclear cell fraction was analyzed for cEPC by FACS analysis, and SDF-1α was analyzed by ELISA. The study population was... Tipo: Info:eu-repo/semantics/article Palavras-chave: Chemotherapy; Circulating endothelial progenitor cells; Multiple myeloma. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000800736 Registros recuperados: 1 Primeira ... 1 ... Última

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