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	Provedor de dados BJID (1) BJPS (1) Autor Zhang,Shu (2) Cao,Guangxiang (1) Cheng,Yanna (1) Deng,Hong (1) Fanpu,Ji (1) Huang,Na (1) Huang,Xiaojing (1) Li,Zongfang (1) Wang,Fengshan (1) Zhong,Chuanqing (1) Mais... Palavra-chave Antiviral therapy (1) Heparin-superoxide dismutase conjugate (1) Hepatitis C virus (1) Oxidative stress injury (1) Radiation-induced damage (1) Splenectomy (1) Thrombocytopenia (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2017 (1) 2013 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Splenectomy prior to antiviral therapy in patients with hepatitis C virus related decompensated cirrhosis BJID Fanpu,Ji; Zhang,Shu; Huang,Na; Deng,Hong; Li,Zongfang. Patients with hepatitis C virus-related decompensated cirrhosis can benefit frominterferonbased antiviral therapy, but the common complication of cytopenia is a contraindication for this treatment. Splenectomy prior to interferon therapy may alleviate this problem. To investigate whether splenectomy improves the efficacy of antiviral therapy, 13 interferonnaïve hepatitis C virus decompensated cirrhotic patients underwent splenectomy between January 2008 and January 2011, followed 1-3 months later by an interferon-based therapeutic regimen (pegylated/standard interferon-α combined with ribavirin for 48 weeks). Ten (76.9%) of the patients developed postoperative complications, which included minor portal vein thrombosis (2/13, 15.4%) and transient ascites... Tipo: Info:eu-repo/semantics/other Palavras-chave: Hepatitis C virus; Thrombocytopenia; Splenectomy; Antiviral therapy. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500014 The radiation protection role of heparin-SOD conjugate in irradiated mice BJPS Zhong,Chuanqing; Huang,Xiaojing; Zhang,Shu; Cheng,Yanna; Cao,Guangxiang; Wang,Fengshan. ABSTRACT Heparin-SOD conjugate (Hep-SOD) was prepared by modifying Cu,Zn-SOD with heparin. An acute radiation-induced mouse injury model was constructed to study the radiation protection effects of Hep-SOD conjugate. Fifty-six mice were randomly divided into seven groups: (I) normal control group; (II) irradiated control group; (III) positive control group (amifostine group, 300 mg/kg); (IV) SOD group (35000 U/kg); (V) high dosage of Hep-SOD group (70000 U/kg); (VI) medium dosage of Hep-SOD group (35000 U/kg); (VII) low dosage of Hep-SOD group (17500 U/kg). Drugs were intraperitoneally injected into each mouse 1 h before radiation except for the normal control group. All the irradiated groups were irradiated with 6 Gy. Organ indices, haematopoietic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Heparin-superoxide dismutase conjugate; Radiation-induced damage; Oxidative stress injury. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400611 Registros recuperados: 2 Primeira ... 1 ... Última

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