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	Provedor de dados BJMBR (1) Genet. Mol. Biol. (1) Autor Zhong,Yang (2) Chen,Jian Yu (1) Gao,Hong (1) Lei,Yidong (1) Li,Jian Shui (1) Liu,Zhi (1) Shi,Suhua (1) Tsering,Tashi (1) Xie,Liang (1) Mais... Palavra-chave Genetic diversity (1) Hengduan Mountains region (1) Hepatocellular carcinoma MEG3 (1) ISSR (1) MiR-9-5p SOX11 lncRNA (1) Rhodiola crenulata (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2019 (1) 2006 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última lncRNA MEG3 inhibits the growth of hepatocellular carcinoma cells by sponging miR-9-5p to upregulate SOX11 BJMBR Liu,Zhi; Chen,Jian Yu; Zhong,Yang; Xie,Liang; Li,Jian Shui. The long non-coding RNA (lncRNA) maternally expressed gene 3 (MEG3), a tumor suppressor, is critical for the carcinogenesis and progression of different cancers, including hepatocellular carcinoma (HCC). To date, the roles of lncRNA MEG3 in HCC are not well illustrated. Therefore, this study used western blot and qRT-PCR to evaluate the expression of MEG3, miR-9-5p, and Sex determining Region Y-related HMG-box 11 (SOX11) in HCC tissues and cell lines. RNA pull-down and luciferase reporter assay were used to evaluate these molecular interactions. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and flow cytometry detected the viability and apoptosis of HCC cells, respectively. The results showed that MEG3 and SOX11 were poorly expressed but... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatocellular carcinoma MEG3; MiR-9-5p SOX11 lncRNA. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019001000604 Determination of genetic variation in Rhodiola crenulata from the Hengduan Mountains Region, China using inter-simple sequence repeats Genet. Mol. Biol. Lei,Yidong; Gao,Hong; Tsering,Tashi; Shi,Suhua; Zhong,Yang. The plant Rhodiola crenulata is a perennial herbaceous species distributed in the plateau region of southwestern China, especially the Hengduan Mountains region. It has been one of the most important traditional herbal remedies in Tibet for more than one thousand years, but the accelerated and uncontrolled collection of this plant since the 1980s has lead to deforestation. We used inter-simple sequence repeats (ISSR) to assess levels of genetic variation in R. crenulata from nine diverse natural populations in eastern Tibet and northern Yunnan, the first time such a study has been carried out. The 12 primers we used were able to detect 184 polymorphic loc. Analysis of molecular variance (AMOVA) indicated that species level genetic diversity was relatively... Tipo: Info:eu-repo/semantics/article Palavras-chave: Genetic diversity; Hengduan Mountains region; ISSR; Rhodiola crenulata. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000200023 Registros recuperados: 2 Primeira ... 1 ... Última

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