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Prakash,; Singh,Gajendra; Singh,Sukh Mahendra. |
The present study assessed central nervous system (CNS) and immune system changes in murine fetuses after cyclophosphamide (CP) exposure during intrauterine life. A single CP dose of 0, 10, or 20mg/kg body weight was administered by intraperitoneal inj ection to pregnant mice (20/group) on day 11 of gestation (GD 11) and fetuses were evaluated on day 19 of gestation (GD 19). Fetuses were examined for external changes, and then the brains and thymuses were removed for further evaluations of histological changes, protein content, apoptotic cell count, DNA fragmentation, and in vitro cell proliferation using 1 fetus/litter for each assessment. Brains and thymuses from CP-exposed fetuses were smaller in size and distorted in overall shape compared to those... |
Tipo: Journal article |
Palavras-chave: Cyclophosphamide; Brain; Thymus; Mice; Teratology. |
Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400016 |
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Prakash,; Prabhu,Latha V; Vadgaonkar,Rajanigandha; Pai,Mángala M; Ranade,Anu V; Singh,Gajendra. |
This comprehensive anatomical study on bones and X-rays regarding pedicles of lumbar vertebrae was performed in two parts. In the first part of the present work direct gross measurements of 3 different diameters (v, d, and 1) of both the pedicles of LI to L5 vertebrae (200 male and 200 female) were recorded through sliding vernier caliper. In the second part plain anteroposterior radiographs of the lumbar spine from 500 individuals (250 males and 250 females) were collected, and divided in 6 age groups and 2 different diameters (t and h) were recorded. The minimum horizontal diameter (d) of both the pedicles increased from LI to L5. Whereas, the vertical height (v) of both the pedicles increased from LI to L2, decreased from L2 to L3 and increased from L3... |
Tipo: Journal article |
Palavras-chave: Pedicle; Vertebra lumbar; Spine; Morphometry. |
Ano: 2007 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200026 |
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