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| Pilipović,I.; Kosec,D.; Radojević,K.; Perišić,M.; Pešić,V.; Stojić-Vukanić,Z.; Leposavi,G.. |
| There is evidence that the major mediators of stress, i.e., catecholamines and glucocorticoids, play an important role in modulating thymopoiesis and consequently immune responses. Furthermore, there are data suggesting that glucocorticoids influence catecholamine action. Therefore, to assess the putative relevance of glucocorticoid-catecholamine interplay in the modulation of thymopoiesis we analyzed thymocyte differentiation/maturation in non-adrenalectomized and andrenalectomized rats subjected to treatment with propranolol (0.4 mg·100 g body weight-1·day-1) for 4 days. The effects of β-adrenoceptor blockade on thymopoiesis in non-adrenalectomized rats differed not only quantitatively but also qualitatively from those in adrenalectomized rats. In... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Catecholamines; Glucocorticoids; Β-adrenoceptors; Propranolol; Thymocyte apoptosis; Thymocyte proliferation; Thymocyte differentiation. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300009 |
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