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	Provedor de dados BABT (1) Autor Li,Shanshan (1) Tang,Xiaobo (1) Wang,Zhigang (1) Yu,Lei (1) Zhang,Rong (1) Zhu,Daling (1) Mais... Palavra-chave 15-hydroxyeicosatetraenoic acid (1) Hypoxia (1) Pulmonary artery rings (1) Pulmonary artery smooth muscle cells (1) [ Ca2+]i (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2008 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Influence of the 15-HETE on cytosolic [ Ca2+] i of the rabbit pulmonary artery smooth muscle cells BABT Tang,Xiaobo; Zhang,Rong; Wang,Zhigang; Yu,Lei; Li,Shanshan; Zhu,Daling. Extracellular Ca2+ influx was blocked by L-type Ca2+ channel blocker nifedipine to observe the effects of 15-hydroxyeicosatetraenoic acid on the constriction of rabbit pulmonary artery rings and on the changes of Ca2+ level in the rabbit pulmonary artery smooth muscle cells, and further to investigate the mechanism of the calcium mobilization induced by the 15-HETE under hypoxic conditions. The effect of extracellular Ca2+ on tension of the rabbit PA rings was also studied. Nifedipine (10 µ mol/L) had no effect on 1 µ mol/L 15-hydroxyeicosatetraenoic acid induced vasoconstriction under normoxic and hypoxic conditions. Intracellular Ca2+ increased markedly in the 15-HETE group (cells were exposed to 1 µ mol/L 15-HETE for 8 min during culture) compared to... Tipo: Info:eu-repo/semantics/article Palavras-chave: 15-hydroxyeicosatetraenoic acid; Hypoxia; Pulmonary artery rings; Pulmonary artery smooth muscle cells; [ Ca2+]i. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000200007 Registros recuperados: 1 Primeira ... 1 ... Última

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