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da Rosa,H.S.; Salgueiro,A.C.F.; Colpo,A.Z.C.; Paula,F.R.; Mendez,A.S.L.; Folmer,V.. |
Sida tuberculata (Malvaceae) is a medicinal plant traditionally used in Brazil as an antimicrobial and anti-inflammatory agent. Here, we aimed to investigate the different extractive techniques on phytochemical parameters, as well as to evaluate the toxicity and antioxidant capacity of S. tuberculata extracts using in silico and in vitro models. Therefore, in order to determine the dry residue content and the main compound 20-hydroxyecdysone (20E) concentration, extracts from leaves and roots were prepared testing ethanol and water in different proportions. Extracts were then assessed by Artemia salina lethality test, and toxicity prediction of 20E was estimated. Antioxidant activity was performed by DPPH and ABTS radical... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sida tuberculata; 20-hydroxyecdysone; Toxicity prediction; Antioxidant. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000800602 |
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Festucci-Buselli,Reginaldo A.; Contim,Luis A. S.; Barbosa,Luiz Cláudio A.; Stuart,Jeff J.; Vieira,Roberto F.; Otoni,Wagner C.. |
The ecdysteroid 20-hydroxyecdysone (20E) is a steroid hormone found in insects and few plants. To analyze its temporal and spatial distribution in Pfaffia glomerata (Amaranthaceae), we selected among 71 accessions, the accession 13 which showed the highest root 20E total quantity (1.48 g/plant root). The 20E was constantly detected in flowers, leaves, stems, and roots, but its percentage was variable throughout its development. The highest 20E percentage was found in flowers (0.82%), roots (0.66%), leaves (0.60%), and stems (0.24%). While stems showed the least variable 20E percentage (0.13% - 0.24%), followed by roots (0.42% - 0.66%), and flowers (0.47% - 0.82%). Leaves showed the greatest 20E percentage variation (0.21%... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pfaffia glomerata (Spreng.) Pedersen; Amaranthaceae; Brazilian ginseng; Phytochemical analysis; Terpenes; Phytoecdysteroid; 20-hydroxyecdysone. |
Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-04202008000400006 |
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