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	Provedor de dados BJPS (1) Autor AnjiReddy,Keshireddy (1) Karpagam,Subramanian (1) Palavra-chave 3D atomic force microscopy (1) Alzheimer’s disease (1) Donepezil (1) Nanocrystalline cellulose (1) Oral dispersible film (1) Solvent casting (1) Ultrasonication (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2020 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Micro and nanocrystalline cellulose based oral dispersible film; preparation and evaluation of in vitro/in vivo rapid release studies for donepezil BJPS AnjiReddy,Keshireddy; Karpagam,Subramanian. Oral fast-dispersible film was prepared by utlizing donepezil hydrochloride (drug) and various cellulose derivatives such as hydroxypropyl methyl cellulose (hypermellose) (HPMC), microcrystalline cellulose (MCC) and nanocrystalline cellulose (NCC) to treat Alzheimer’s disease. NCC was synthesized by ultra-sonication method using MCC and this was converted to thinfilm formulation (NCC-F) using solvent casting technique. The interaction between the polymer and the drug was investigated by spectral analysis such as UV, FTIR, and 1H- NMR. FTIR confirmed that the compatibility of drug and polymer in ODF formulation. NCC-F has shown an average surface roughness of 77.04 nm from AFM and the average particle size of 300 nm from SEM analysis. Nano sized particle of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Oral dispersible film; Nanocrystalline cellulose; Ultrasonication; 3D atomic force microscopy; Donepezil; Solvent casting; Alzheimer’s disease. Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100586 Registros recuperados: 1 Primeira ... 1 ... Última

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