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| Horta,Roberta Nunes; Kahl,Vivian Francilia Silva; Sarmento,Merielen da Silva; Nunes,Marisa Fernanda Silva; Porto,Carem Rejane Maglione; Andrade,Vanessa Moraes de; Ferraz,Alexandre de Barros Falcão; Silva,Juliana Da. |
| Abstract Metal ions such as iron can induce DNA damage by inducing reactive oxygen species (ROS) and oxidative stress. Vitamin C is one of the most widely consumed antioxidants worldwide, present in many fruits and vegetables, especially inMalpighia glabra L., popularly known as acerola, native to Brazil. Acerola is considered a functional fruit due to its high antioxidant properties and phenolic contents, and therefore is consumed to prevent diseases or as adjuvant in treatment strategies. Here, the influence of ripe and unripe acerola juices on iron genotoxicity was analyzed in vivo using the comet assay and micronucleus test. The comet assay results showed that acerola juice exerted no genotoxic or antigenotoxic activity. Neither ripe nor unripe acerola... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Genotoxicity; Comet assay; Micronucleus; Acerola juice; Iron. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000100122 |
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