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| Tanaka,K.; Shigueoka,E.M.; Sawatani,E.; Dias,G.A.; Arashiro,F.; Campos,T.C.X.B.; Nakao,H.C.. |
| Large volumes of plasma can be fractionated by the method of Cohn at low cost. However, liquid chromatography is superior in terms of the quality of the product obtained. In order to combine the advantages of each method, we developed an integrated method for the production of human albumin and immunoglobulin G (IgG). The cryoprecipitate was first removed from plasma for the production of factor VIII and the supernatant of the cryoprecipitate was fractionated by the method of Cohn. The first precipitate, containing fractions (F)-I + II + III, was used for the production of IgG by the chromatographic method (see Tanaka K et al. (1998) Brazilian Journal of Medical and Biological Research, 31: 1375-1381). The supernatant of F-I + II + III was submitted to a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Albumin production; Industrial chromatography; Hemoderivate production; Downstream process; Plasma derivatives. |
| Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998001100003 |
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