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| Pinto,Isadora Cabral; Cerqueira-Coutinho,Cristal; Freitas,Zaida Maria Faria de; Santos,Elisabete Pereira dos; Carmo,Flávia Almada do; Ricci Junior,Eduardo. |
| ABSTRACT Diseases caused by insects are frequent in poor countries, leading to epidemic scenarios in urban areas; e.g., Dengue, Zika and Chikungunya. For this reason, the development of a safe and efficient topical formulation is essential. Ethyl butylacetylaminopropionate (EB) is a mosquito repellent developed by Merck, which is used in products for adults, children and especially babies, due to its low allergenic potential. The aim of this work was to validate an analytical methodology to quantify EB in a new poloxamer-based formulation by high-performance liquid chromatography (HPLC). The quantification methodology was performed at 40 ºC using a Kromasil reverse-phase column (C18), with the dimensions of 250 x 4.6 mm. The mobile phase was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ethyl butylacetylaminopropionate (EB)/quantification; Ethyl butylacetylaminopropionate (EB)/topical formulations; Analytical method; Validation; Repellents; Prophylaxis; High Performance Liquid Chromatography.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000200613 |
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| Soares,Liliane Catone; Egreja Filho,Fernando Barboza; Windmoller,Cláudia Carvalhinho; Yoshida,Maria Irene. |
| Despite the considerable environmental importance of mercury (Hg), given its high toxicity and ability to contaminate large areas via atmospheric deposition, little is known about its activity in soils, especially tropical soils, in comparison with other heavy metals. This lack of information about Hg arises because analytical methods for determination of Hg are more laborious and expensive compared to methods for other heavy metals. The situation is even more precarious regarding speciation of Hg in soils since sequential extraction methods are also inefficient for this metal. The aim of this paper is to present a technique of thermal desorption associated with atomic absorption spectrometry, TDAAS, as an efficient tool for quantitative determination of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Heavy metal; Analytical method; Weathered soils. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-06832015000401100 |
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