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Wang,H.H.; Wang,Q.F.. |
Vaspin is a novel adipocytokine associated with glucose tolerance and chronic inflammation. Some studies reveal that vaspin may be involved in cardiovascular diseases. Our objective was to investigate the relationship between serum vaspin levels and endothelial function in patients with ankylosing spondylitis. One hundred and twenty patients with newly diagnosed ankylosing spondylitis and 100 healthy subjects were studied. Serum vaspin levels were measured with enzyme-linked immunosorbent assay. High resolution ultrasound was used to measure brachial artery diameter at rest, after reactive hyperemia (flow-mediated dilation, FMD) and after sublingual glyceryltrinitrate. Serum vaspin level in patients was 1.92±1.03 ng/mL, which was significantly lower than... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vaspin; Endothelial function; Ankylosing spondylitis. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000700705 |
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Oliveira Junior,Haliton Alves de; Almeida,Alessandra Maciel; Acurcio,Francisco Assis; Santos,Jéssica Barreto dos; Kakehasi,Adriana Maria; Alvares,Juliana; Dabés,Clarice Gomes e Souza; Cherchiglia,Mariangela Leal. |
The aim of this study was to describe the baseline demographic and clinical characteristics as well as the functional status of a prospective cohort of patients with rheumatic diseases assisted by the Brazilian Public Health System (SUS). Data for 302 patients receiving tumor necrosis factor α inhibitors (anti-TNF agents) was collected through a standard form. Among patients, 229 (75.8%) were female and 155 (51.3%) were Caucasian; the mean age was 50.3 ± 12.8 years, and the mean disease duration was 9.9 ± 8.7 years. Among them 214 patients (70.9%) received adalimumab, 72 (23.8%) etanercept, and 16 (5.3%) infliximab. Mean Health Assessment Questionnaire-Disability Index (HAQ-DI) was 1.37 ± 0.67 for all participants. Poor functional response was associated... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rheumatic diseases/treatment/patients profile; Rheumatoid arthritis; Ankylosing spondylitis; Psoriatic arthritis; Brazilian public health system; Anti-TNF agents/treatment of rheumatic diseases. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502015000300709 |
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