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Occult B infection in the Brazilian northeastern region: a preliminary report BJID
Almeida,Delvone; Tavares-Neto,José; Trepo,Christian; Almeida,Alessandro; Mello,Caroline; Chemin,Isabelle; Paraná,Raymundo.
A sentinel study on viral hepatitis is currently being carried out in the village of Cavunge in a semiarid rural region of the state of Bahia, northeastern Brazil. This study has identified individuals in whom anti-HBc IgG was the only serological marker for hepatitis B virus (HBV). This serological pattern may constitute evidence of occult HBV infection. This study Investigated the possibility of occult hepatitis B virus infection in individuals in a rural community who tested positive for anti-HBc IgG alone. A cross-sectional population-based study. ELISA III was performed on serum samples to test for serological viral markers, and ultrasensitive PCR (US-PCR) was used to assess viremia. Among the 1,536 serum samples, 3.6% (n=55) were positive for...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Anti-HBc alone; Hepatitis B virus; Occult hepatitis B; Ultrasensitive PCR.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400010
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Occult hepatitis B virus infection in immunocompromised patients BJID
Jardim,Ruth Nogueira Cordeiro Moraes; Gonçales,Neiva Sellan Lopes; Pereira,Josiane Silveira Felix; Fais,Viviane Cristina; Gonçales Junior,Fernando Lopes.
Occult hepatitis B infection is characterized by hepatitis B virus (HBV) DNA in the serum in the absence of hepatitis B surface antigen (HBsAg). We assessed occult HBV infection prevalence in two groups of immunocompromised patients (maintenance hemodialysis patients and HIV-positive patients) presenting HBsAg-negative and anti-HBc positive serological patterns, co-infected or not by HCV. Thirty-four hemodialysis anti-HIV negative patients, 159 HIV-positive patients and 150 blood donors who were anti-HBc positive (control group) were selected. HBV-DNA was detected by nested-PCR. Occult hepatitis B infection was not observed in the hemodialysis patients group but was found in 5% of the HIV-patients and in 4% of the blood donors. Immunosuppression in HIV...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Occult HBV infection; HBV-DNA; Anti-HBc alone; Hemodialysis; HIV; Immunosupressed patients.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400008
Registros recuperados: 2
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