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	Provedor de dados BJID (1) BJMBR (1) Autor Almeida,Thereza Lúcia P. (1) Brasil,Márcia (1) Ferreira,M.A.N. (1) Foss,N.T. (1) Lima,Ana Laura P. (1) Nagao-Dias,Aparecida T. (1) Oliveira,Maria de Fátima (1) Santos,Rivanda C. (1) Zenha,E.M.R. (1) Mais... Palavra-chave Anti-PGL-1 (2) Leprosy (2) Avidity (1) MDT 12 months (1) MDT 24 months (1) Multidrug therapy (1) Salivary antibodies (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2009 (1) 2007 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Salivary anti-PGL IgM and IgA titers and serum antibody IgG titers and avidities in leprosy patients and their correlation with time of infection and antigen exposure BJID Nagao-Dias,Aparecida T.; Almeida,Thereza Lúcia P.; Oliveira,Maria de Fátima; Santos,Rivanda C.; Lima,Ana Laura P.; Brasil,Márcia. The present work proposed to correlate serum antibody avidity and salivary antibody titers as parameters for time of infection and antigen exposure in a co-hort study evaluating leprosy patients in different periods of treatment. Colorimetric enzyme-immunoassays for salivary antibodies, serum antibody IgG titers and avidities were performed in the samples. Anti-PGL-1 IgA and IgM salivary antibodies were significantly higher in multibacillar (MB-L) patients compared to normal controls (p<0.05), but not when compared to borderline tuberculoid (BT) or to paucibacillar (PB-L) patients (p>0.05). A good correlation was found between salivary anti-PGL-1 IgA and IgM levels in MB-L patients (r=0.41, p<0.01). Two out of 33 tested saliva samples from... Tipo: Info:eu-repo/semantics/article Palavras-chave: Anti-PGL-1; Avidity; Leprosy; Salivary antibodies. Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000200009 Use of anti-PGL-1 antibodies to monitor therapy regimes in leprosy patients BJMBR Zenha,E.M.R.; Ferreira,M.A.N.; Foss,N.T.. The suitability of IgM antibodies to PGL-1 for monitoring the response to multidrug therapy (MDT) was sequentially tested by ELISA in 105 leprosy patients, and bacterial indexes (BI) were also determined. Patients were divided into 3 groups: group 1, 34 multibacillary (MB) patients treated for 12 months with MDT-MB; group 2, 33 MB patients treated for 24 months with MDT-MB, and group 3, 38 paucibacillary (PB) patients treated for 6 months with MDT-PB. Untreated MB patients exhibited higher antibody levels (mean ± SEM): group 1 (6.95 ± 1.35) and group 2 (12.53 ± 2.02) than untreated PB patients (1.28 ± 0.35). There was a significant difference (P < 0.01) in anti-PGL-1 levels in group 1 patients: untreated (6.95 ± 1.35) and treated for 12 months (2.78 ±... Tipo: Info:eu-repo/semantics/article Palavras-chave: Leprosy; Anti-PGL-1; Multidrug therapy; MDT 12 months; MDT 24 months. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000016 Registros recuperados: 2 Primeira ... 1 ... Última

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