Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados Anais da ABC (AABC) (1) ArchiMer (1) BJMBR (1) Rev. Bras. Frutic. (1) Autor Agustine,P.E. (1) Boillot, C. (1) Bueno, M. J. Martinez (1) Casellas, C. (1) DRONJAK,SLADJANA (1) Do Monte,F.H.M. (1) Estrada-Reyes,Rosa (1) Fenet, H. (1) Gomez, E. (1) JOVANOVIC,PREDRAG (1) Lanziotti,V.M.N.B. (1) Martínez-Vázquez,Mariano (1) Munaron, Dominique (1) Russi,M. (1) SPASOJEVIC,NATASA (1) Santos Junior,J.G. (1) Mais... Palavra-chave Antidepressant (4) Adrenal medulla (1) Alkaloids (1) Annona sp. (1) Convulsion (1) Emerging contaminants (1) Epilepsy (1) Gene expression (1) Marine organisms (1) Norepinephrine transporter (1) Orbitrap (1) Pentylenetetrazole (1) QuEChERS (1) Transformation products (1) Tyrosine hydroxylase (1) Venlafaxine (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Info:eu-repo/semantics/other (1) Text (1) Ano 2015 (1) 2014 (2) 2002 (1) País Brazil (3) France (1) Idioma Inglês (4)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Occurrence of venlafaxine residues and its metabolites in marine mussels at trace levels: development of analytical method and a monitoring program ArchiMer Bueno, M. J. Martinez; Boillot, C.; Munaron, Dominique; Fenet, H.; Casellas, C.; Gomez, E.. Coastal areas are subject to growing pressures and impacts due to increasing of the human activities. Lipophilic organic contaminants, such as polycyclic aromatic hydrocarbons (PAHs) or polychlorinated biphenyls (PCBs), have been monitored for decades within biomonitoring programs. However, until now, little information on the detection of called “emerging contaminants” as hydrophilic organic compounds, in the marine environment and no data on its metabolites or transformation products in marine organisms is available. In this way, a sensitive analytical methodology for identification and confirmation of venlafaxine residues (VEN) and five of its main metabolites in the marine mussels Mytilus galloprovincialis was validated. The sample preparation... Tipo: Text Palavras-chave: Antidepressant; Emerging contaminants; Transformation products; Marine organisms; Orbitrap; QuEChERS. Ano: 2014 URL: http://archimer.ifremer.fr/doc/00168/27877/26123.pdf Secondary metabolismin in Annonaceae: potencial source of drugs Rev. Bras. Frutic. Martínez-Vázquez,Mariano; Estrada-Reyes,Rosa. Several species of Annona (Annonaceae) are used in traditional Mexican medicine by their anti-anxiety, anticonvulsant and tranquilizing properties. It has been reported that the alkaloids isolated from some species of the Annona have affinity to serotonergic 5-HT1A receptors and modulate dopaminergic transmission, which is involved in depressive disorders. In this review it is showed the results of the antidepressant-like effect of an alkaloid extract from the aerial parts of Annona cherimola (TA) in mice. The antidepressant-like effect was evaluated in the forced swimming test. To elucidate a possible mechanism of action, experiments of synergism with antidepressant drugs, such as imipramine (IMI), clomipramine (CLIMI), and fluoxetine (FLX), were carried... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antidepressant; Alkaloids; Annona sp.. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452014000500017 Differential regulation of catecholamine synthesis and transport in rat adrenal medulla by fluoxetine treatment Anais da ABC (AABC) SPASOJEVIC,NATASA; JOVANOVIC,PREDRAG; DRONJAK,SLADJANA. We have recently shown that chronic fluoxetine treatment acted significantly increasing plasma norepinephrine and epinephrine concentrations both in control and chronically stressed adult male rats. However, possible effects of fluoxetine on catecholamine synthesis and re-uptake in adrenal medulla have been largely unknown. In the present study the effects of chronic fluoxetine treatment on tyrosine hydroxylase, a rate-limiting enzyme in catecholamine synthesis, as well as a norepinephrine transporter and vesicular monoamine transporter 2 gene expressions in adrenal medulla of animals exposed to chronic unpredictable mild stress (CUMS) for 4 weeks, were investigated. Gene expression analyses were performed using a real-time quantitative reverse... Tipo: Info:eu-repo/semantics/article Palavras-chave: Adrenal medulla; Antidepressant; Gene expression; Norepinephrine transporter; Tyrosine hydroxylase. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100343 Proconvulsant effects of high doses of venlafaxine in pentylenetetrazole-convulsive rats BJMBR Santos Junior,J.G.; Do Monte,F.H.M.; Russi,M.; Agustine,P.E.; Lanziotti,V.M.N.B.. Venlafaxine, an atypical antidepressant drug, has been used to treat several neurological disorders, presenting excellent efficacy and tolerability. Clinical seizures after venlafaxine treatment have occasionally been reported when the drug was used at very high doses or in combination with other medications. The aim of the present study was to investigate the convulsant effects of venlafaxine in rats under controlled laboratory conditions. Adult male Wistar rats (8 per group) receiving venlafaxine or saline at the doses of 25-150 mg/kg were subjected 30 min later to injections of pentylenetetrazole at the dose of 60 mg/kg. The animals receiving 75, 100 and 150 mg/kg venlafaxine presented increased severity of convulsion when compared to controls (P =... Tipo: Info:eu-repo/semantics/other Palavras-chave: Antidepressant; Venlafaxine; Convulsion; Epilepsy; Pentylenetetrazole. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400010 Registros recuperados: 4 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco