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| Pal,Savita; Mishra,Arvind; Rawat,Arun Kumar; Gautam,Sudeep; Maurya,Rakesh; Srivastava,Arvind K.. |
| The present study was undertaken to investigate the antidiabetic potential of tap roots of Potentilla fulgens in streptozotocin induced diabetic rat models. The crude powder, ethanolic, ethanolic: aqueous and aqueous extracts of tap roots were administered to normoglycemic- and streptozotocin (STZ)-induced diabetic rats in a single dose study. The ethanolic extract showed significant improvement in oral glucose tolerance and antihyperglycemic effect on sucrose loaded normal rats and STZ-induced diabetic rats. Of the isolated aqueous, n-butanol, chloroform and n-hexane soluble fractions of the active ethanolic extract of the roots, the aqueous fraction (100 mg/kg body weight) showed significant blood glucose lowering effect on STZ-induced diabetic rats. In... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antidiabetic activity; Antihyperglycemic Activity; Antidyslipidemic activity; Potentilla fulgens roots; Alpha (α)-glucosidase enzyme. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100318 |
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| Ozbek,Hanefi; Acikara,Ozlem Bahadir; Oz,Burcin Ergene; Ozbilgin,Serkan; Kirmizi,Neriman Ipek; Ozrenk,Bade Cevriye; Tekin,Mehmet; Saltan,Gulcin. |
| In the current study, four Onobrychis species, O. albiflora Hub.-Mor., O. argyrea Boiss. subsp. argyrea Boiss., O. galegifolia Boiss., and O. tournefortii (Willd.) Desv. were collected from Anatolia to be evaluated for their antidiabetic activities. Methanol water extracts of the aerial parts were used for experiments. An alloxan-induced diabetic mice test model was used. Phytochemical analysis of the tested extracts was investigated using the HPLC method. The highest activity was observed with treatment of O. albiflora aerial part extract. Significant decrements were detected in the blood glucose levels as follows: 180.83±47.48 and 252.83±50.47mg/dL at 100 mg/kg and 200 mg/kg doses of O. albiflora, respectively, when compared to the isotonic saline... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Onobrychis; Antidiabetic activity; Alloxan; Rutin; Isoquercetin; Phytochemical analysis.. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100504 |
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