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	Provedor de dados BJPS (2) BJMBR (1) Autor Alves,P.H. (1) Castro,C.H. (1) Colugnati,D.B. (1) Dwivedi,Harinath (1) Macedo,L.M. (1) Mendes,E.P. (1) Nunes,A.D.C. (1) Pathak,Kamla (1) Pedrino,G.R. (1) Porwal,Amit (1) Rocha,Aline Pereira (1) Santos,Brigitte Rieckmann Martins dos (1) Santos,R.A.S. (1) Souza,A.P.S. (1) Mais... Palavra-chave Antihypertensive drugs (3) Angiotensin-(1-7) (1) Antihypertensive medications/use (1) Bio/mucoadhesive systems (1) Cardiac hypertrophy (1) Coronary artery (1) Drug therapy/adherence to treatment (1) Drugs/continuous use (1) Expanding and swelling systems (1) Floating systems (1) Gastroretention delivery systems/absorption (1) Hypertension (1) Medicines/benefit manegement (1) Renin-angiotensin system (1) Treatment adherence (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2017 (2) 2011 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Influence of antihypertensive drugs on aortic and coronary effects of Ang-(1-7) in pressure-overloaded rats BJMBR Nunes,A.D.C.; Souza,A.P.S.; Macedo,L.M.; Alves,P.H.; Pedrino,G.R.; Colugnati,D.B.; Mendes,E.P.; Santos,R.A.S.; Castro,C.H.. This study investigated the influence of antihypertensive drugs, such as angiotensin-converting enzyme inhibitors (ACEIs), AT1 receptor blockers (ARBs), voltage-gated L-type calcium channel blockers, and mineralocorticoid receptor antagonists (MRAs), on the effects of angiotensin-(1-7) [Ang-(1-7)] on aorta and coronary arteries from pressure-overloaded rats. Pressure overload was induced by abdominal aortic banding (AB). To evaluate the role of antihypertensive drugs on the effect of Ang-(1-7), AB male Wistar rats weighing 250–300 g were treated with vehicle or low doses (5 mg·kg-1·day-1, gavage) of losartan, captopril, amlodipine, or spironolactone. Isolated aortic rings and isolated perfused hearts under constant flow were used to evaluate the effect of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Angiotensin-(1-7); Renin-angiotensin system; Coronary artery; Antihypertensive drugs; Cardiac hypertrophy. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000400604 Decades of research in drug targeting using gastroretentive drug delivery systems for antihypertensive therapy BJPS Porwal,Amit; Dwivedi,Harinath; Pathak,Kamla. ABSTRACT The limitations in absorption of drugs with narrow absorption window, or those unstable in the intestinal pH or those exhibiting low solubility at high pH are primary candidates for gastroretentive drug delivery systems (GRDDS). The delivery system has been widely explored for its commercial potential for a wide variety of therapeutic agents. GRDDS offer clinical therapeutics for acute and chronic management. Hypertension is a chronic disease that requires long term treatment and its management by patient compliant dosage forms would be clinically useful. Antihypertensives belonging to different classes have proved good candidates for the formulation of GRDDS. The review aims to discuss various GRDDS researched for antihypertensive drugs to... Tipo: Info:eu-repo/semantics/article Palavras-chave: Antihypertensive drugs; Gastroretention delivery systems/absorption; Floating systems; Expanding and swelling systems; Bio/mucoadhesive systems. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300401 Consumption of antihypertensive drugs dispensed under the pharmacy benefit management program BJPS Rocha,Aline Pereira; Santos,Brigitte Rieckmann Martins dos. Pharmacy benefit management (PBM) programs provide attractive discounts for drug purchase, a relevant measure to address costs, mainly of drugs for the treatment of chronic diseases. This study investigated whether PBM may be used as a tool to provide information about the use of antihypertensive medications when they are purchased. The profile of medicines taken to treat high blood pressure by large IT company employees and their dependents was evaluated from January to December 2009. The mean rate of drug boxes purchased to control hypertension was 9.4 ± 10.0 in 2009. Men purchased more drugs than women. The number of drugs purchased for the treatment of hypertension was lower than expected in all age groups except for individuals aged 54-58 and >59... Tipo: Info:eu-repo/semantics/article Palavras-chave: Hypertension; Antihypertensive drugs; Drugs/continuous use; Antihypertensive medications/use; Treatment adherence; Drug therapy/adherence to treatment; Medicines/benefit manegement. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000400018 Registros recuperados: 3 Primeira ... 1 ... Última

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