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| Registros recuperados: 119 | |
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| SILVA,Emily Marcele Soares; SILVA,Ingrid Reis da; OGUSKU,Mauricio Morishi; CARVALHO,Clarice Maia; MAKI,Cristina Sayuri; PROCÓPIO,Rudi Emerson de Lima. |
| ABSTRACT Tuberculosis (TB) remains one of the most deadly communicable infectious diseases, causing 1.4 million deaths in 2015 worldwide due to many conditions, including the inadequate treatment and the emergence of multidrug-resistant strains of the causal agent, Mycobacterium tuberculosis. Therefore, drugs developed from natural sources, as microorganisms and plant extracts, are a frequent target for the research and discovery of antimicrobial compounds. The current study started the characterization of compounds produced by an Aspergillus fumigatus isolated from copaíba (Copaifera multijuga) that efficiently inhibits M. tuberculosis by releasing the compounds into the fermentation broth under specific culture conditions. A preliminary assay was carried... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mycobacterium spp.; Antimicrobial activity; Copaíba; Chromatography. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672018000100063 |
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| Lund, Rafael Guerra; Universidade Federal de Pelotas; Serpa, Rosana; Universidade Federal de Pelotas; Nascente, Patrícia da Silva; Universidade Federal de Pelotas; Ribeiro, Gladis Aver; Universidade Federal de Pelotas; Freitag, Rogério Antonio; Universidade Federal de Pelotas; Del Pino, Francisco Augusto Burkert; Universidade Federal de Pelotas. |
| In vitro tests could be a valuable tool for the evaluation of medicinal plants’ antimicrobial activity. Mentha arvensis of the Lamiaceae family is one of the most frequently traditional plants used in Brazil. Hydroalcoholic extracts of M. arvensis were analyzed for antimicrobial activity on Streptococcus mutans, Streptococcus sobrinus and Candida albicans. Three different assays (agar diffusion, broth macro- and micro-dilution methods) were used to evaluate antimicrobial activity. Although hydroalcoholic extracts of M. arvensis did not show any antibacterial effect, its antifungal activity against C. albicans was revealed. According to the micro-dilution broth assay, MIC of the hydroalcoholic extract from leaves of M. arvensis on Candida albicans strains... |
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Palavras-chave: 2.12.00.00-9 Microbiologia Mentha arvensis; Antimicrobial activity; Streptococcus mutans; Candida albicans Microbiologia. |
| Ano: 2012 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/8959 |
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| Corrêa, Paulo Roberto Ceridório; UEL; Pinto, Artur da Silveira; UFMG; Silva, Grácia Divina de Fátima; UFMG; Vieira Filho, Sidney Augusto; UFOP; Duarte, Lucienir Pains; UFMG; Yamada-Ogatta, Sueli Fumie; UEL. |
| The effect of 2-pyridinecarboxylic acid (picolinic acid) on trypanosomes of the subgenus Schizotrypanum isolated from the bat Phyllostomus hastatus was determined in this study. Picolinic acid, at 50 µg mL-1, inhibited epimastigote growth by 99% after 12 days incubation. In addition, trypomastigote motility decreased by 50% after 6h and completely after 24h in the presence of 50 µg mL-1 picolinic acid. The 50% cytotoxic concentration on HEp-2 cell line was 275 µg mL-1 after 4 days incubation. Altogether, these results indicate higher toxicity against trypanosomes. The inhibitory effect of picolinic acid on epimastigote growth can be partially reversed by nicotinic acid and L-tryptophan, suggesting a competitive inhibition.... |
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Palavras-chave: Ciências Biológicas; Microbiologia; 2.12.02.00-1 bat trypanosome; Schizotrypanum; 2-pyridinecarboxylic acid; Antimicrobial activity Atividade antimicrobiana bat trypanosome; Schizotrypanum; 2-pyridinecarboxylic acid; Antimicrobial activity. |
| Ano: 2011 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/6482 |
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| Azimi Mahalleh, Afsaneh; Sharayei, Parvin; Mortazavi, Seyed Ali; Azarpazhooh, Elham; Niazmand, Razieh. |
| Pulsed electric field (PEF) treatment was used for extracting effective components from Nepeta (Nepeta binaludensis Jamzad). A response surface method was used to investigate the effects of independent process variables (voltage of pulsed electric field (VPEF): 2, 4 and 6 KV/cm and number of pulsed electric field (NPEF): 20, 40 and 60 n) on the yield (Y) and antioxidant characteristics: total phenolic compounds (TPC), 1,1- diphenyl -2- picrylhydrazyl free radical scavenging (DPPHsc), ferric reducing-antioxidant power (FRAP), half maximal of radical-scavenging activity (IC50) of Nepeta extract (aerial parts). According to Derringer’s desired function approach, the optimal conditions based on both individual and combinations of all process variables were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phenolic compounds; Nepeta binaludensis; Response Surface Methodology; Pulsed electric field; Antimicrobial activity. |
| Ano: 2019 |
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/5391 |
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| Azimi Mahalleh, Afsaneh; Sharayei, Parvin; Mortazavi, Seyed Ali; Azarpazhooh, Elham; Niazmand, Razieh. |
| Pulsed electric field (PEF) treatment was used for extracting effective components from Nepeta (Nepeta binaludensis Jamzad). A response surface method was used to investigate the effects of independent process variables (voltage of pulsed electric field (VPEF): 2, 4 and 6 KV/cm and number of pulsed electric field (NPEF): 20, 40 and 60 n) on the yield (Y) and antioxidant characteristics: total phenolic compounds (TPC), 1,1- diphenyl -2- picrylhydrazyl free radical scavenging (DPPHsc), ferric reducing-antioxidant power (FRAP), half maximal of radical-scavenging activity (IC50) of Nepeta extract (aerial parts). According to Derringer’s desired function approach, the optimal conditions based on both individual and combinations of all process variables were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phenolic compounds; Nepeta binaludensis; Response Surface Methodology; Pulsed electric field; Antimicrobial activity. |
| Ano: 2019 |
URL: http://www.cigrjournal.org/index.php/Ejounral/article/view/5391 |
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| SIRAKANYAN,SAMVEL N.; GERONIKAKI,ATHINA; SPINELLI,DOMENICO; HAKOBYAN,ELMIRA K.; KARTSEV,VIKTOR G.; PETROU,ANTHI; HOVAKIMYAN,ANUSH A.. |
| ABSTRACT Annulated thienopyrimidine derivatives attracted big interest of the scientific community due to their broad spectrum of biological activities among which are the inhibition of phosphodiesterase, antiproliferative and antimicrobial activities. As a continuation of our studies on the synthesis and biological activity of fused thieno[3,2-d]pyrimidine derivatives, the goal of this paper is the synthesis and study of the properties of compounds containing different heterocycles such as fused thieno[2,3-b]pyridine and tetrazolo[1,5-c]pyrimidine in the same molecule. Thus, starting from the ethyl 1-amino-5-isopropyl-8,8-dimethyl-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxylate 1, efficient methods for obtaining new... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amino derivatives; Antimicrobial activity; Azide/tetrazole equilibrium; Nucleophilic substitution; Thieno[3; 2-d]pyrimidine. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000301043 |
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| PEREIRA,RAFAEL; PEREIRA,ANNA L.; FERREIRA,MARCILIO M.; FONTENELLE,RAQUEL O.S.; SAKER-SAMPAIO,SILVANA; SANTOS,HÉLCIO S.; BANDEIRA,PAULO N.; VASCONCELOS,MAYRON A.; QUEIROZ,JOSÉ A.N.; BRAZ-FILHO,RAIMUNDO; TEIXEIRA,EDSON H.. |
| Abstract: This study evaluated the antibacterial, antifungal, and antioxidant effect of 7-hydroxy-4’,6-dimethoxy-isoflavone and essential oil of Myroxylon peruiferum. The compound was isolated and its structure elucidated by NMR. The chemical composition of essential oil determined by GC-MS analysis. To evaluation of antimicrobial activity, the Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) were performed. In addition to analysis of antioxidant activity, DPPH radical scavenging tests, iron chelating assay (FIC), antioxidant reducing power assay (FRAP) and β-carotene bleaching assay (BCB) were performed. For the essential oil were identified 24 organized compounds having as main... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial activity; Antioxidant activity; Essential oil; Isoflavone; Myroxylon peruiferum. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300602 |
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| Nascimento,Jeferson C.; Barbosa,Luiz C.A.; Paula,Vanderlucia F.; David,Jorge M.; Fontana,Renato; Silva,Luiz A.M.; França,Robson S.. |
| This work describes the chemical composition and antimicrobial activity of the volatile oils of Ocimum canum and Ocimum selloi, both occurring in Jequié/BA, northeastern Brazil. The plants were collected in the winter/2005 andsummer/2006, the oils extracted by steam distillation and further analyzed by GC-MS. A total of 30 and 31 compounds was identified from the oils of O. selloi and O. canum, respectively. It was observed that the oil content of O. canum showed variation during the seasons, while the oils of O. selloi did not. Methylchavicol and linalool were the main chemical components found in the aerial parts and leaves of O. canum. This finding permitted to characterize this specimen as a new chemotype of O. canum. Regarding the aerial parts of O.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial activity; Essential oil; Lamiaceae; Ocimum canum; Ocimum selloi. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000300004 |
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| ALPAY,MERVE; DULGER,GORKEM; SAHIN,IBRAHIM E.; DULGER,BASARAN. |
| Abstract: In this study, the antimicrobial, antioxidant and antitumor activity of ethanol extracts obtained from Phlomis russeliana (Sims.) Lag. ex Benth. (Lamiaceae) were evaluated. Disc diffusion and microdilution methods were used to test the extracts for antimicrobial activity against seven bacteria strains (Bacillus cereusATCC 7064, Bacillus subtilisATCC 6633, Staphylococcus aureusATCC 6538P, Escherichia coliATCC 10538, Proteus vulgarisATCC 6899, Salmonella typhimuriumCCM 5445 and Pseudomonas aeruginosaATCC 27853) and four yeast strains (Kluyveromyces fragilisATCC 8608, Rhodotorula rubraATCC 70403, Debaryomyces hanseniiDSM 70238 and Candida albicansATCC 10239). Notably, they were more effective against the yeast strains than the bacterial strains. Of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phlomis russeliana; Antioxidant activity; Cytotoxic effect; Antimicrobial activity; Endemic plant. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500604 |
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| AKINPELU,DA; ADEGBOYE,MF; ADELOYE,OA; OKOH,AI. |
| The in vitro antibacterial activity of crude methanolic extract of the seeds of Garcinia kola was investigated. The extracts exhibited antibacterial activities with zones of inhibition ranging from 10 mm to 25 mm. The minimum inhibitory concentration of the diethyl ether fraction was between 0.313 and 5.0 mg/ml, while that of butanol fraction varied from 0.157 to 5.0 mg/ml. The butanol fraction killed about 77% of Bacillus anthracis and 79% of Escherichia coli cells within 120 min at a concentration of 5.0 mg/ml. Protein leakage from the B. anthracis and E. coli cells when exposed to the butanol and diethyl ether fractions was observed. We conclude that Garcinia kola seed extract has a broad spectrum antibacterial activity, with the butanol and diethyl... |
| Tipo: Journal article |
Palavras-chave: Garcinia kola; Antimicrobial activity; MIC; Killing rate; Protein leakage. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000300005 |
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| Hossain,Mohammad Mobarak; Ahamed,Sayed Koushik; Dewan,Syed Masudur Rahman; Hassan,Md Mahadi; Istiaq,Arif; Islam,Mohammad Safiqul; Moghal,Md Mizanur Rahman. |
| BACKGROUND: The study was conducted to evaluate the in vitro antimicrobial activity, cytotoxic, and membrane stabilization activities, and in vivo antiemetic and antipyretic potentials of ethanolic extract, n-hexane and ethyl acetate soluble fractions of Spilanthes paniculata leaves for the first time widely used in the traditional treatments in Bangladesh. RESULTS: In antipyretic activity assay, a significant reduction (P < 0.05) was observed in the temperature in the mice tested. At dose 400 mg/kg-body weight, the n-hexane soluble fraction showed the effect (36.7 ± 0.63°C ) as like as the standard (dose 150 mg/kg-body weight) after 5 h of administration. Extracts showed significant (P < 0.001) potential when tested for the antiemetic activity... |
| Tipo: Journal article |
Palavras-chave: Antiemetic; Anti-inflammatory; Antimicrobial activity; Brine shrimp lethality bioassay; Cytotoxic; Membrane stabilization; Spilanthes paniculata. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100045 |
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| Cóndor-Luján,Báslavi; Francia-Quiroz,Juan C.. |
| ABSTRACT In the last decades, sponges have emerged as the largest source of active compounds of animal origin for pharmaceutical purposes. In Peru information on these animals is incipient and scattered, which limits taking the right measures for their adequate management, exploitation, and conservation. The aim of this study is to provide an update on the scope and perspectives of sponge research in Peru, with an emphasis on species richness and their antibacterial potential. Likewise, research initiatives carried out in other South American Pacific countries are reviewed. Research efforts in Peru have allowed the description of 46 species; however, the sponge richness is underestimated. On the other hand, in other latitudes, active principles with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antimicrobial activity; Bacteria; Biotechnology; Marine biodiversity; Porifera.. |
| Ano: 2022 |
URL: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0122-97612022000200107 |
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| Ferreira,Alessandra Einsfeld; Canal,Natália; Morales,Daiana; Fuentefria,Daiane Bopp; Corção,Gertrudes. |
| The aim of this study was to characterize bacteriocins produced by 70 strains of Enterococcus mundtii.Four strains exhibited antibiotic activity towards Listeria innocua, L. monocytogenes, Lactobacillus plantarum, and Salmonella Enteritidis. They remained active under temperatures of up to 121ºC for 20 min, and under pH treatments that varied from 2.0 to 10.0. Antimicrobial activity was maintained during the storage test for 60 days under freezing. The kinetics of production revealed the peak activity of 1600 AU /mL during the logarithmic growth phase and the molecular weight found was approximately 3.0 kDa. The characterization of the products with antimicrobial activity indicated their proteic nature, presenting a typical kinetics of primary metabolite... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Enterococcus mundtii; Enterocins; Antimicrobial activity; Biopreservative. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132007000200010 |
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| Tayung,Kumanand; Sarkar,Meenakshi; Baruah,Paran. |
| The aim of this work was to study the endophytic fungi associated with the tissues of Ipomoea carnea, a common invasive plant of India. A total of 69 isolates belonging to ten taxa comprising 1.45% Zygomycetes, 10.14% Coelomycetes, 62.32% Hypomycetes, 18.84% sterile mycelia and 7.25% unidentified species were obtained. Species of Curvularia, Aspergillus, Fusarium, Colletotrichum and sterile fungus were isolated as dominant endophytes. Colonization frequency of Curvularia (7.25%) was highest which was isolated from all the tissues. The samples collected during the monsoon harbored more endophytes and showed higher species richness than the samples obtained in summer season. Of the total isolates, 15 isolates (21.74%) displayed antimicrobial activity,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ipomoea carnea; Endophytic fungi; Curvularia; Antimicrobial activity. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000500003 |
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| Gerige,Saptha Jyothi; Gerige,Mahesh Kumar Yadav; Rao,Muralidhara; Ramanjaneyulu,. |
| The present study dealt with the hydro distillation of Nigella sativa seeds and GC-MS analysis. The total composition of the oil was 86.7%. The seed volatile oil was tested against 19 microbes (Gram positive, Gram negative and fungi), which showed that Gram negative bacteria Haemophilus influenza, Klebsiella pnemoniae, and Proteus vulgaris were highly sensitive against the antimicrobial agent, whereas the fungi such as Trichoderma vibriae,. Pencillium rubrum; and Dermatophyte: Trichophyton mentagrophytes; had no response at the 20µl concentration. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nigella sativa; Volatile oil; Antimicrobial activity; Antifungal activity. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000500016 |
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| Carvalho,André Lacerda Ulysses de; Oliveira,Fábio Henrique Portella Corrêa de; Mariano,Rosa de Lima Ramos; Gouveia,Ester Ribeiro; Souto-Maior,Ana Maria. |
| The physiology of B. subtilis R14 was investigated in minimal medium under excess-oxygen and oxygen-limited conditions. Growth and efficient sporulation could be achieved in excess-oxygen culture on medium with readily metabolizable carbon and nitrogen sources, which allowed high growth rate and high biomass yield. A short transition phase between the exponential growth and sporulation could be attained by formulating a medium with a well-balanced C/N ratio. Under oxygen-limitation, but in the presence of essential nutrients (i.e. excess-nutrient cultivation), B. subtilis R14 produced bioactive compounds, which showed activity against several phytopathogenic bacteria. Under anaerobic condition, the organism did not grow neither through fermentation nor... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bacillus subtilis; Batch cultivation; Oxygen availability; Antimicrobial activity. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000300020 |
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| Registros recuperados: 119 | |
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