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| Shahrivar,Farzaneh Faraji; Badavi,Mohammad; Dianat,Mahin; Mard,Ali; Ahangarpour,Akram; Hedayati,Mehdi; Samarbaf-zadeh,Alireza. |
| Atherosclerosis is one of the common disorders among hypothyroidism, which, increased the risk of cardiovascular diseases. Reactive oxygen species are associated with atherosclerosis development. Antioxidant defense systems are the scavenger for free radicals. Apelin is an endogenous ligand for the APJ receptor (apelin receptor) that exists in most tissues, acts as an adiponectin. It has been identified that apelin administration, improve the antioxidant capacity (TAC). Therefore, this study was conducted to assess, therapeutic effects of apelin, T4 (L-Thyroxin) or both on antioxidant capacity in 6-propyl-2-thiouracil (PTU)-induced hypothyroid rats. Forty male Wistar rats were randomly assigned into five groups: C: control group; P group (hypothyroid): PTU... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Apelin; Antioxidative; Hypothyroid; Rat; Thyroxin. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100308 |
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| Dai,Xin; Zhou,Ling-Yu; Xu,Ting-Ting; Wang,Qiu-Yue; Luo,Bin; Li,Yan-Yu; Gu,Chen; Li,Shi-Ping; Wang,Ai-Qin; Wei,Wan-Hong; Yang,Sheng-Mei. |
| ABSTRACT Tannins are polyphenols that are present in various plants, and potentially contain antioxidant properties that promote reproduction in animals. This study investigated how tannic acid (TA) affects the reproductive parameters of male Brandt’s voles, Lasiopodomys brandtii (Radde, 1861). Specifically, the anti-oxidative level of serum, autophagy in the testis, and reproductive physiology were assessed in males treated with TA from the pubertal stage. Compared to the control, low dose TA enhanced relative testis and epididymis weight and sperm concentration in the epididymis, and significantly increased the level of serum superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px). mRNA levels of autophagy related genes LC3 and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antioxidative; Autophagy; Puberty; Reproduction. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702020000100319 |
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