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	Provedor de dados BABT (1) Autor Bandehpour,Mojgan (1) Kazemi,Bahram (1) Milani,Saeideh (1) Sharifi,Zohreh (1) Palavra-chave Apollon (1) Apoptosis (1) Cervical cancer (1) Radiosensitivity (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2016 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última The Role of Apollon Gene Silencing on Viablity and Radiosensitivity of Cervical Cancer Hela Cells BABT Milani,Saeideh; Bandehpour,Mojgan; Sharifi,Zohreh; Kazemi,Bahram. Cervical cancer is the second common cause of cancer deaths in women worldwide. Radioresistancy of cancer is a principal cause of treatment impairing. Inhibitor of apoptosis proteins (IAPs) widely block apoptosis against apoptotic stimuli, including current chemo- and radiation therapies. Apollon, a membrane of IAP, can support cells against apoptosis and is over expressed in some treatment-resistant cancer cells. The aim of this study was to evaluate the effects of apollon knockdown on induction of apoptosis and also its potential for enhancement of radiosensitvity on hela cells. plasmid encoding shRNA which has been confirmed its effect against apollon, transfected into hela cells. Consequent effects on the level of P53 , Bax and BAK analyzed by real... Tipo: Info:eu-repo/semantics/article Palavras-chave: Apollon; Apoptosis; Radiosensitivity; Cervical cancer. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100320 Registros recuperados: 1 Primeira ... 1 ... Última

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