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| Belarmino,Luis C.; Oliveira,Ana R. da S.; Brasileiro-Vida,Ana C.; Bortoleti,Kyria C. de A.; Bezerra-Neto,João Pacífico; Abdelnoor,Ricardo V.; Benko-Iseppon,Ana M.. |
| Physical maps are important tools to uncover general chromosome structure as well as to compare different plant lineages and species, helping to elucidate genome structure, evolution and possibilities regarding synteny and colinearity. The increasing production of sequence data has opened an opportunity to link information from mapping studies to the underlying sequences. Genome browsers are invaluable platforms that provide access to these sequences, including tools for genome analysis, allowing the integration of multivariate information, and thus aiding to explain the emergence of complex genomes. The present work presents a tutorial regarding the use of genome browsers to develop targeted physical mapping, providing also a general overview and examples... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gene families; FISH; BAC; SSR; Aquaporin; Bioinformatics. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000200015 |
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| GALLARDO,PEDRO; HERRERA,SOFÍA; SAFFER,KARIN; BOZINOVIC,FRANCISCO. |
| Rodents from arid and semiarid environments live under conditions where the spatial and temporal availability of water is limited. Octodon degus is a South-American desert-dwelling rodent inhabiting arid and semiarid habitats of central and northern Chile. Its survival depends on morphological, physiological and behavioral adaptations that allow water conservation. This rodent has a high urine concentrating ability, high capacity of fecal dehydration and low evaporative water loss, related to the ability of the nasal passages to condense water from the exhaled air; this water must be absorbed in order to avoid its accumulation in the nasal passages and potential loss through the nostrils. We hypothesize that aquaporins (AQPs) might be present in the nasal... |
| Tipo: Journal article |
Palavras-chave: Aquaporin; Nasal passage; Desert rodent. |
| Ano: 2008 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2008000100003 |
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| Peng,Tianzhong; Huang,Xuedi; Hu,Suifa; Xie,Gui; Zhou,Cheng; Xiong,Jia; Liu,Rui. |
| ABSTRACT This study aimed to investigate the expression and mechanism of N- methyl -D- aspartate receptor 1 (NMDAR1) in the pathogenesis of Alzheimer disease (AD). Eighty adult Wistar rats were randomly divided into 4 groups (n=20 each) to receive an injection of 0, 5, 7 and 10 μl of 1 μg/μl amyloid-β 42 (Aβ1-42) in the hippocampus. Twenty rats in normal control group were injected with equal volume of saline. After 10 days, the hippocampus was isolated from 5 randomly selected rats in each group. The NMDAR1 protein and mRNA expression was determined by immunohistochemical staining and qRT-PCR. The aquaporin-1 (AQP-1) mRNA expression was also measured by qRT-PCR. We found that both NMDAR1 and AQP-1 expression in Aβ1-42 groups was increased in a... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: NMDAR1; Alzheimer disease; Aquaporin; AQP-1. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100435 |
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