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Upregulation of lncRNA BANCR associated with the lymph node metastasis and poor prognosis in colorectal cancer Biol. Res.
Shen,Xiaogang; Bai,Yifeng; Luo,Bin; Zhou,Xiaogang.
Abstract Background Growing evidence has supported that long non-coding RNAs (lncRNAs) could play vital roles in the development, progression, and prognosis of colorectal cancer (CRC). However, little is known about the clinical significance of BRAF-activated non-coding RNA (BANCR) in CRC. The aim of this study is to explore the clinical value of lncRNA BANCR in CRC patients. Methods The expression of lncRNA BANCR was measured in 106 CRC tissues and 65 adjacent normal tissues using the quantitative real-time PCR. Results The study showed that lncRNA BANCR was highly expressed in CRC tissues compared with adjacent normal tissues (P < 0.001). In addition, high expression of lncRNA BANCR was positively correlated with the lymph node metastasis (P...
Tipo: Journal article Palavras-chave: LncRNA; BANCR; Colorectal cancer; Lymph node metastasis; Prognosis.
Ano: 2017 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602017000100223
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